@article{3a5e3dc5cf044e29a705ca3bc5b1225c,
title = "Mouse models of preterm birth: Suggested assessment and reporting guidelines",
abstract = "Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences. To investigate the mechanisms leading to preterm birth so as to develop prevention strategies, researchers have developed numerous mouse models of preterm birth. However, the lack of standard definitions for preterm birth in mice limits our field's ability to compare models and make inferences about preterm birth in humans. In this review, we discuss numerous mouse preterm birth models, propose guidelines for experiments and reporting, and suggest markers that can be used to assess whether pups are premature or mature. We argue that adoption of these recommendations will enhance the utility of mice as models for preterm birth.",
keywords = "gestation, mouse models, parturition, pregnancy, preterm birth",
author = "Ronald McCarthy and Carmel Martin-Fairey and Sojka, {Dorothy K.} and Herzog, {Erik D.} and Jungheim, {Emily S.} and Stout, {Molly J.} and Fay, {Justin C.} and Mala Mahendroo and Jeff Reese and Herington, {Jennifer L.} and Plosa, {Erin J.} and Shelton, {Elaine L.} and England, {Sarah K.}",
note = "Funding Information: 1Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA; 2Rheumatology Division, Washington University School of Medicine, St. Louis, Missouri, USA; 3Department of Biology, Washington University in St. Louis, St. Louis, Missouri, USA; 4Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA; 5Department of Biology, University of Rochester, Rochester, New York, USA; 6Department of Obstetrics and Gynecology University of Texas Southwestern Medical Center, Dallas, Texas, USA and 7Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA ∗Correspondence: Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, 425 South Euclid Avenue, Campus Box 8064, St. Louis, MO 63110. Tel: +(314) 286–1798; Fax: +(314) 747–4150; E-mail: englands@wustl.edu †Grant support: This review was supported by NIH grants HD081121 (to JR), HD088830 (to JLH), and HL132805 (to ELS), and the March of Dimes Prematurity Research Center (to EDH, ESJ, JCF, MM, and SKE). SKE is supported by the Department of Obstetrics and Gynecology at Washington University and the March of Dimes Prematurity Research Center. Publisher Copyright: {\textcopyright} The Author(s) 2018. Published by Oxford University Press on behalf of Society for the Study of Reproduction.",
year = "2018",
month = nov,
day = "1",
doi = "10.1093/biolre/ioy109",
language = "English (US)",
volume = "99",
pages = "922--937",
journal = "Biology of reproduction",
issn = "0006-3363",
publisher = "Society for the Study of Reproduction",
number = "5",
}