Abstract
Moxalactam was given to 136 women for treatment of uterine infections after cesarean delivery. After an intravenous loading dose of 2 g, 36 women received 3 g daily and 100 were given 6 g daily. The clinical success rates of these two regimens were 86% and 89%, respectively; however, in four of five women for whom treatment with the 3-g daily dose failed, extensive surgery was necessary for cure. A total of 395 pathogens was isolated from these women with polymicrobial infections, and almost 90% were susceptible to moxalactam at less than or equal to 32 micrograms/ml. Adverse effects of therapy were minimal. Thus, moxalactam given initially as a dosage of 6 g daily is effective for treatment of women with pelvic infections after cesarean delivery.
| Original language | English (US) |
|---|---|
| Journal | Reviews of Infectious Diseases |
| Volume | 4 Suppl |
| State | Published - Nov 1982 |
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ASJC Scopus subject areas
- Microbiology (medical)
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Moxalactam for treatment of pelvic infections after cesarean delivery. / Cunningham, F. G.; Gibbs, R. S.; Hemsell, D. L.
In: Reviews of Infectious Diseases, Vol. 4 Suppl, 11.1982.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Moxalactam for treatment of pelvic infections after cesarean delivery.
AU - Cunningham, F. G.
AU - Gibbs, R. S.
AU - Hemsell, D. L.
PY - 1982/11
Y1 - 1982/11
N2 - Moxalactam was given to 136 women for treatment of uterine infections after cesarean delivery. After an intravenous loading dose of 2 g, 36 women received 3 g daily and 100 were given 6 g daily. The clinical success rates of these two regimens were 86% and 89%, respectively; however, in four of five women for whom treatment with the 3-g daily dose failed, extensive surgery was necessary for cure. A total of 395 pathogens was isolated from these women with polymicrobial infections, and almost 90% were susceptible to moxalactam at less than or equal to 32 micrograms/ml. Adverse effects of therapy were minimal. Thus, moxalactam given initially as a dosage of 6 g daily is effective for treatment of women with pelvic infections after cesarean delivery.
AB - Moxalactam was given to 136 women for treatment of uterine infections after cesarean delivery. After an intravenous loading dose of 2 g, 36 women received 3 g daily and 100 were given 6 g daily. The clinical success rates of these two regimens were 86% and 89%, respectively; however, in four of five women for whom treatment with the 3-g daily dose failed, extensive surgery was necessary for cure. A total of 395 pathogens was isolated from these women with polymicrobial infections, and almost 90% were susceptible to moxalactam at less than or equal to 32 micrograms/ml. Adverse effects of therapy were minimal. Thus, moxalactam given initially as a dosage of 6 g daily is effective for treatment of women with pelvic infections after cesarean delivery.
UR - http://www.scopus.com/inward/record.url?scp=0020215844&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020215844&partnerID=8YFLogxK
M3 - Article
VL - 4 Suppl
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
ER -