Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy

D. Hemsell, P. Hemsell, B. Nobles, M. Heard, R. Bawdon

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Moxalactam is a newer β-lactam antibiotic with increased activity and an extended antimicrobial spectrum. Three 1 gm doses were given to women scheduled for elective vaginal hysterectomy. This perioperative regimen was prospectively compared to identical doses of cefazolin, a first-generation cephalosporin of proved efficacy. The overall incidence of major postoperative infection in 193 women was <5% and there were no significant interregimen differences. The incidence of major infection was directly related to the type of procedure performed.

Original languageEnglish (US)
Pages (from-to)379-385
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume147
Issue number4
StatePublished - 1983

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Moxalactam
Vaginal Hysterectomy
Cefazolin
Lactams
Incidence
Cephalosporins
Infection
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Hemsell, D., Hemsell, P., Nobles, B., Heard, M., & Bawdon, R. (1983). Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy. American Journal of Obstetrics and Gynecology, 147(4), 379-385.

Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy. / Hemsell, D.; Hemsell, P.; Nobles, B.; Heard, M.; Bawdon, R.

In: American Journal of Obstetrics and Gynecology, Vol. 147, No. 4, 1983, p. 379-385.

Research output: Contribution to journalArticle

Hemsell, D, Hemsell, P, Nobles, B, Heard, M & Bawdon, R 1983, 'Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy', American Journal of Obstetrics and Gynecology, vol. 147, no. 4, pp. 379-385.
Hemsell, D. ; Hemsell, P. ; Nobles, B. ; Heard, M. ; Bawdon, R. / Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy. In: American Journal of Obstetrics and Gynecology. 1983 ; Vol. 147, No. 4. pp. 379-385.
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