Moxalactam versus cefazolin prophylaxis for vaginal hysterectomy

D. Hemsell, P. Hemsell, B. Nobles, M. Heard, R. Bawdon

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Moxalactam is a newer β-lactam antibiotic with increased activity and an extended antimicrobial spectrum. Three 1 gm doses were given to women scheduled for elective vaginal hysterectomy. This perioperative regimen was prospectively compared to identical doses of cefazolin, a first-generation cephalosporin of proved efficacy. The overall incidence of major postoperative infection in 193 women was <5% and there were no significant interregimen differences. The incidence of major infection was directly related to the type of procedure performed.

Original languageEnglish (US)
Pages (from-to)379-385
Number of pages7
JournalUnknown Journal
Issue number4
StatePublished - 1983

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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