MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet

Neil M. Rofsky, Ben M. Yang, Peter Schlossberg, Alec Goldenberg, Lewis W. Teperman, Jeffrey C. Weinreb

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Purpose: Our purpose was to assess the efficacy of MR-guided biopsies with a conventional superconducting MR scanner and describe the techniques used to achieve successful results. Method: Fourteen biopsies were completed under MR guidance in 11 patients. Seven patients with previously detected lesions were referred for biopsy under MR guidance when hepatic lesions were identified by MRI but not with prebiopsy noncontrast CT or ultrasound (US). Additionally referred for MR-guided biopsy were four patients in whom previous CT- or US-guided biopsies of focal lesions were nondiagnostic. A 22 gauge MR-compatible needle was used in each case. Lesions ranged in size from 8 to 32 mm. Eleven lesions (eight patients) were suspected of being hepatomas, and three lesions (three patients) were suspected of being metastases. Results: Thirteen of 14 MR-guided biopsies (93%) were diagnostic. Hepatocellular carcinoma was confirmed in 6 of 11 lesions suspected of representing hepatoma. One lesion, in a patient treated with chemoembolization, demonstrated necrotic material. One lesion yielded nondiagnostic material despite repeated visualization of the needle tip in the target lesion. Three lesions demonstrated metastatic carcinoma. Benign hepatocytes were detected in three biopsy specimens. Seven of the lesions that were successfully biopsied measured <2.5 cm in diameter. Conclusion: With use of a closed bore 1.5 T system, diagnostic MR-guided needle aspiration biopsies of hepatic masses and subcomponents, including small lesions (<2.5 cm), can be successfully obtained.

Original languageEnglish (US)
Pages (from-to)633-637
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume22
Issue number4
DOIs
StatePublished - 1998

Fingerprint

Magnets
Needle Biopsy
Biopsy
Liver
Hepatocellular Carcinoma
Needles
Hepatocytes
Neoplasm Metastasis
Carcinoma

Keywords

  • Biopsy and biopsies
  • Liver, biopsy
  • Liver, diseases
  • Liver, neoplasms
  • Magnetic resonance imaging, techniques.
  • Magnetic resonance- guided biopsy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet. / Rofsky, Neil M.; Yang, Ben M.; Schlossberg, Peter; Goldenberg, Alec; Teperman, Lewis W.; Weinreb, Jeffrey C.

In: Journal of Computer Assisted Tomography, Vol. 22, No. 4, 1998, p. 633-637.

Research output: Contribution to journalArticle

Rofsky, Neil M. ; Yang, Ben M. ; Schlossberg, Peter ; Goldenberg, Alec ; Teperman, Lewis W. ; Weinreb, Jeffrey C. / MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet. In: Journal of Computer Assisted Tomography. 1998 ; Vol. 22, No. 4. pp. 633-637.
@article{0ddc5c94b03d47b7ae667d585256dae6,
title = "MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet",
abstract = "Purpose: Our purpose was to assess the efficacy of MR-guided biopsies with a conventional superconducting MR scanner and describe the techniques used to achieve successful results. Method: Fourteen biopsies were completed under MR guidance in 11 patients. Seven patients with previously detected lesions were referred for biopsy under MR guidance when hepatic lesions were identified by MRI but not with prebiopsy noncontrast CT or ultrasound (US). Additionally referred for MR-guided biopsy were four patients in whom previous CT- or US-guided biopsies of focal lesions were nondiagnostic. A 22 gauge MR-compatible needle was used in each case. Lesions ranged in size from 8 to 32 mm. Eleven lesions (eight patients) were suspected of being hepatomas, and three lesions (three patients) were suspected of being metastases. Results: Thirteen of 14 MR-guided biopsies (93{\%}) were diagnostic. Hepatocellular carcinoma was confirmed in 6 of 11 lesions suspected of representing hepatoma. One lesion, in a patient treated with chemoembolization, demonstrated necrotic material. One lesion yielded nondiagnostic material despite repeated visualization of the needle tip in the target lesion. Three lesions demonstrated metastatic carcinoma. Benign hepatocytes were detected in three biopsy specimens. Seven of the lesions that were successfully biopsied measured <2.5 cm in diameter. Conclusion: With use of a closed bore 1.5 T system, diagnostic MR-guided needle aspiration biopsies of hepatic masses and subcomponents, including small lesions (<2.5 cm), can be successfully obtained.",
keywords = "Biopsy and biopsies, Liver, biopsy, Liver, diseases, Liver, neoplasms, Magnetic resonance imaging, techniques., Magnetic resonance- guided biopsy",
author = "Rofsky, {Neil M.} and Yang, {Ben M.} and Peter Schlossberg and Alec Goldenberg and Teperman, {Lewis W.} and Weinreb, {Jeffrey C.}",
year = "1998",
doi = "10.1097/00004728-199807000-00024",
language = "English (US)",
volume = "22",
pages = "633--637",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet

AU - Rofsky, Neil M.

AU - Yang, Ben M.

AU - Schlossberg, Peter

AU - Goldenberg, Alec

AU - Teperman, Lewis W.

AU - Weinreb, Jeffrey C.

PY - 1998

Y1 - 1998

N2 - Purpose: Our purpose was to assess the efficacy of MR-guided biopsies with a conventional superconducting MR scanner and describe the techniques used to achieve successful results. Method: Fourteen biopsies were completed under MR guidance in 11 patients. Seven patients with previously detected lesions were referred for biopsy under MR guidance when hepatic lesions were identified by MRI but not with prebiopsy noncontrast CT or ultrasound (US). Additionally referred for MR-guided biopsy were four patients in whom previous CT- or US-guided biopsies of focal lesions were nondiagnostic. A 22 gauge MR-compatible needle was used in each case. Lesions ranged in size from 8 to 32 mm. Eleven lesions (eight patients) were suspected of being hepatomas, and three lesions (three patients) were suspected of being metastases. Results: Thirteen of 14 MR-guided biopsies (93%) were diagnostic. Hepatocellular carcinoma was confirmed in 6 of 11 lesions suspected of representing hepatoma. One lesion, in a patient treated with chemoembolization, demonstrated necrotic material. One lesion yielded nondiagnostic material despite repeated visualization of the needle tip in the target lesion. Three lesions demonstrated metastatic carcinoma. Benign hepatocytes were detected in three biopsy specimens. Seven of the lesions that were successfully biopsied measured <2.5 cm in diameter. Conclusion: With use of a closed bore 1.5 T system, diagnostic MR-guided needle aspiration biopsies of hepatic masses and subcomponents, including small lesions (<2.5 cm), can be successfully obtained.

AB - Purpose: Our purpose was to assess the efficacy of MR-guided biopsies with a conventional superconducting MR scanner and describe the techniques used to achieve successful results. Method: Fourteen biopsies were completed under MR guidance in 11 patients. Seven patients with previously detected lesions were referred for biopsy under MR guidance when hepatic lesions were identified by MRI but not with prebiopsy noncontrast CT or ultrasound (US). Additionally referred for MR-guided biopsy were four patients in whom previous CT- or US-guided biopsies of focal lesions were nondiagnostic. A 22 gauge MR-compatible needle was used in each case. Lesions ranged in size from 8 to 32 mm. Eleven lesions (eight patients) were suspected of being hepatomas, and three lesions (three patients) were suspected of being metastases. Results: Thirteen of 14 MR-guided biopsies (93%) were diagnostic. Hepatocellular carcinoma was confirmed in 6 of 11 lesions suspected of representing hepatoma. One lesion, in a patient treated with chemoembolization, demonstrated necrotic material. One lesion yielded nondiagnostic material despite repeated visualization of the needle tip in the target lesion. Three lesions demonstrated metastatic carcinoma. Benign hepatocytes were detected in three biopsy specimens. Seven of the lesions that were successfully biopsied measured <2.5 cm in diameter. Conclusion: With use of a closed bore 1.5 T system, diagnostic MR-guided needle aspiration biopsies of hepatic masses and subcomponents, including small lesions (<2.5 cm), can be successfully obtained.

KW - Biopsy and biopsies

KW - Liver, biopsy

KW - Liver, diseases

KW - Liver, neoplasms

KW - Magnetic resonance imaging, techniques.

KW - Magnetic resonance- guided biopsy

UR - http://www.scopus.com/inward/record.url?scp=0031715089&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031715089&partnerID=8YFLogxK

U2 - 10.1097/00004728-199807000-00024

DO - 10.1097/00004728-199807000-00024

M3 - Article

C2 - 9676459

AN - SCOPUS:0031715089

VL - 22

SP - 633

EP - 637

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

IS - 4

ER -