MR imaging of the breast with rotating delivery of excitation off resonance: Clinical experience with pathologic correlation

Steven E. Harms, Duane P. Flamig, Kerri L. Hesley, Mark D. Meiches, Richard A. Jensen, W. P. Evans, Daniel A. Savino, Robert V. Wells

Research output: Contribution to journalArticle

625 Scopus citations

Abstract

An investigative study was undertaken to determine the potential for a new magnetic resonance (MR) imaging technique, RODEO (rotating delivery of excitation off resonance), for use as a diagnostic imaging tool for the breast. The RODEO technique provides fat suppression with T1 weighting and is ideal for gadolinium-enhanced breast imaging. It is a short repetition time, steady-state sequence for high-resolution three-dimensional acquisitions and provides a clinically efficient imaging time of approximately 5 minutes for 128 sections. Imaging findings were correlated with serially sectioned pathologic specimens in 30 breasts with 47 malignant and 27 benign lesions. MR imaging had a sensitivity of 94% and a specificity of 37%. MR imaging depicted additional cancers not seen at mammography in 11 of the 30 patients (37%). The lesions not seen at mammography varied in size from 3 mm to 12 cm. RODEO MR imaging may be used to improve diagnosis of breast cancer in patients with mammographically dense breasts or silicone implants/injections and to stage disease in patients who are candidates for lumpectomy.

Original languageEnglish (US)
Pages (from-to)493-501
Number of pages9
JournalRadiology
Volume187
Issue number2
DOIs
StatePublished - May 1993

Keywords

  • Breast neoplasms, MR, 00.31, 00.32
  • Breast, diseases, 00.72
  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), pulse sequences

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Harms, S. E., Flamig, D. P., Hesley, K. L., Meiches, M. D., Jensen, R. A., Evans, W. P., Savino, D. A., & Wells, R. V. (1993). MR imaging of the breast with rotating delivery of excitation off resonance: Clinical experience with pathologic correlation. Radiology, 187(2), 493-501. https://doi.org/10.1148/radiology.187.2.8475297