Abstract
Purpose: To provide normal biometry of the cerebellar vermis using fetal MR and determine threshold values associated with abnormal neurologic outcome. Materials and Methods: Cerebellar vermis biometry was applied in prospective, cross-sectional evaluation of fetal brains. Vermis length and inferior vermian distance were obtained in mid-sagittal planes using T2-weighted, single-shot sequences with 1.5 Tesla MR. Measurements were compared with reference nomograms from a retrospective review of fetal brains with normal intracranial anatomy. Observed and predicted measurements of the cerebellar vermis were recorded. Neurologic outcome was classified as normal or abnormal. Unpaired t-tests and discriminate analysis were applied to the two measurements and differences between the observed and predicted values. Results: The reference group included 64 fetuses of 13 to 38 weeks gestation. Both vermis length and inferior vermian distance increased linearly with time (r=0.92, P
| Original language | English (US) |
|---|---|
| Journal | Journal of Magnetic Resonance Imaging |
| DOIs | |
| State | Accepted/In press - 2016 |
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Keywords
- Biometry
- Cerebellum
- Fetal
- MRI
- Neurology
- Vermis
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
MR imaging of the fetal cerebellar vermis : Biometric predictors of adverse neurologic outcome. / Xi, Yin; Brown, Emily; Bailey, April; Twickler, Diane M.
In: Journal of Magnetic Resonance Imaging, 2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MR imaging of the fetal cerebellar vermis
T2 - Biometric predictors of adverse neurologic outcome
AU - Xi, Yin
AU - Brown, Emily
AU - Bailey, April
AU - Twickler, Diane M.
PY - 2016
Y1 - 2016
N2 - Purpose: To provide normal biometry of the cerebellar vermis using fetal MR and determine threshold values associated with abnormal neurologic outcome. Materials and Methods: Cerebellar vermis biometry was applied in prospective, cross-sectional evaluation of fetal brains. Vermis length and inferior vermian distance were obtained in mid-sagittal planes using T2-weighted, single-shot sequences with 1.5 Tesla MR. Measurements were compared with reference nomograms from a retrospective review of fetal brains with normal intracranial anatomy. Observed and predicted measurements of the cerebellar vermis were recorded. Neurologic outcome was classified as normal or abnormal. Unpaired t-tests and discriminate analysis were applied to the two measurements and differences between the observed and predicted values. Results: The reference group included 64 fetuses of 13 to 38 weeks gestation. Both vermis length and inferior vermian distance increased linearly with time (r=0.92, P
AB - Purpose: To provide normal biometry of the cerebellar vermis using fetal MR and determine threshold values associated with abnormal neurologic outcome. Materials and Methods: Cerebellar vermis biometry was applied in prospective, cross-sectional evaluation of fetal brains. Vermis length and inferior vermian distance were obtained in mid-sagittal planes using T2-weighted, single-shot sequences with 1.5 Tesla MR. Measurements were compared with reference nomograms from a retrospective review of fetal brains with normal intracranial anatomy. Observed and predicted measurements of the cerebellar vermis were recorded. Neurologic outcome was classified as normal or abnormal. Unpaired t-tests and discriminate analysis were applied to the two measurements and differences between the observed and predicted values. Results: The reference group included 64 fetuses of 13 to 38 weeks gestation. Both vermis length and inferior vermian distance increased linearly with time (r=0.92, P
KW - Biometry
KW - Cerebellum
KW - Fetal
KW - MRI
KW - Neurology
KW - Vermis
UR - http://www.scopus.com/inward/record.url?scp=84963550572&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84963550572&partnerID=8YFLogxK
U2 - 10.1002/jmri.25270
DO - 10.1002/jmri.25270
M3 - Article
C2 - 27086739
AN - SCOPUS:84963550572
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
SN - 1053-1807
ER -