MRI characterization of 124 CT-indeterminate focal hepatic lesions: Evaluation of clinical utility

Khaled M. Elsayes, John R. Leyendecker, Christine O. Menias, Erica P. Oliveira, Vamsidhar R. Narra, William C. Chapman, Moataz H. Hassanien, Mohamed S. Elsharkawy, Jeffrey J. Brown

Research output: Contribution to journalArticle

18 Scopus citations


Objective. To evaluate the diagnostic yield of MRI performed for characterization of focal hepatic lesions that are interpreted as indeterminate on CT. Patients and methods. In a retrospective investigation, 124 indeterminate focal hepatic lesions in 96 patients were identified on CT examinations over 5 years from 1997 to 2001. All patients had MRI performed for the liver within 6 weeks of their CT examination. CT and MR images were reviewed independently by two separate groups of two radiologists. The value of MRI in characterizing these lesions was assessed. Diagnoses were confirmed based on histology, characteristic imaging features, and clinical follow-up. Results. MRI definitely characterized 73 lesions (58%) that were indeterminate on CT. MRI was accurate in 72/73 of these lesions. MRI could not definitely characterize 51 lesions (42%). Ten lesions were not visualized on MRI, and follow-up imaging confirmed that no lesion was present in eight of these cases (pseudolesions). Conclusion. MRI is valuable for the characterization of indeterminate focal hepatic lesions detected on CT.

Original languageEnglish (US)
Pages (from-to)208-215
Number of pages8
Issue number3
Publication statusPublished - Jun 25 2007



  • CT
  • Focal hepatic lesions
  • MRI

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Elsayes, K. M., Leyendecker, J. R., Menias, C. O., Oliveira, E. P., Narra, V. R., Chapman, W. C., ... Brown, J. J. (2007). MRI characterization of 124 CT-indeterminate focal hepatic lesions: Evaluation of clinical utility. HPB, 9(3), 208-215.