MRI evaluation of amyloid myopathy

J. P. Metzler, J. L. Fleckenstein, C. L. White, R. G. Haller, E. P. Frenkel, R. G. Greenlee

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Amyloid myopathy is a rare complication of primary amyloidosis. The magnetic resonance imaging (MRI) features of two patients with amyloid myopathy were studied. Slight prolongation of muscle T1 and T2 relaxation times was evident but the striking abnormality was marked reticulation of the subcutaneous fat. The clinical findings of indurated extremities far exceeds the minimal signal intensity alteration seen in the muscles. The MR appearance of amyloid myopathy differs from that of other neuromuscular conditions in the minimal changes found in muscle, but the striking abnormality seen in subcutaneous fat makes it distinct from many neuromuscular conditions.

Original languageEnglish (US)
Pages (from-to)463-465
Number of pages3
JournalSkeletal radiology
Volume21
Issue number7
DOIs
StatePublished - Oct 1 1992

Keywords

  • Abnormal subcutaneous fat
  • Amyloid pseudohypertrophy
  • Amyloidosis
  • Magnetic resonance imaging
  • Myopathy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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