Mucocutaneous signs of HIV disease: A guide to early detection part 1: Infections and infestations

Shannon N. Matthews, Clay J. Cockerell, Alvin E. Friedman-Kien

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Abstract

The first clinical signs of HIV infection often appear as skin ailments; many of these have unusual features, and some may be life-threatening. Up to half of HIV-infected patients suffer from herpesvirus infection. Herpetic lesions may affect other organs besides the skin, inducting the eye, esophagus, and lung. HIV-seropositive patients exposed to varicella-zoster virus (VZV) must be treated with hyperimmune globulin, VZV vaccine, or high- dose acyclovir. Bacterial skin diseases, such as folliculitis, impetigo, and cellulitis, are common; bacilliary angiomatosis is seen almost exclusively in HIV-infected patients and can mimic Kaposi's sarcoma. Scabies and other ectoparasitic infestations are also frequent; suspect mites if severe, intractable pruritus and a scaly chronic dermatosis are present. Cutaneous fungal infections, such as dermatophytosis, may assume a number of guises; proximal white subungual onychomycosis is seen almost exclusively in immunocompromised patients.

Original languageEnglish (US)
Pages (from-to)2551-2572
Number of pages22
JournalConsultant
Volume37
Issue number10
Publication statusPublished - Oct 1997

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Matthews, S. N., Cockerell, C. J., & Friedman-Kien, A. E. (1997). Mucocutaneous signs of HIV disease: A guide to early detection part 1: Infections and infestations. Consultant, 37(10), 2551-2572.