Mucormycosis: What do emergency physicians need to know?

Brit Long, Alex Koyfman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Mucormycosis is a rare presentation for patients in the emergency department (ED), primarily affecting immunocompromised patients. Multiple forms of infection are present, and with poor prognosis, ED diagnosis and treatment of this deadly condition are necessary. Objective of review: The aim of this review is to provide an overview of the presentations and forms of mucormycosis, diagnosis, and treatment of this deadly disease. Discussion: This review provides background on the fungi causing mucormycosis, which are prevalent in nature. The article discusses the risk factors for infection with mucormycosis, as normal hosts are able to clear the disease, but immunocompromised and diabetic patients are at risk for organism inoculation and spread. The fungi are angioinvasive and cause necrosis. This article describes the various forms of the disease: rhino-orbital-cerebral, pulmonary, central nervous system, gastrointestinal, renal, disseminated, and cutaneous. Finally, this review evaluates diagnosis, treatment, and prognosis. Conclusion: Emergency department diagnosis and treatment are necessary in patients with infection with mucormycosis. Physicians should be suspicious of this disease in immunocompromised and diabetic patients. Treatment requires antifungal agents such as amphotericin B and surgical debridement. Prognosis is poor.

Original languageEnglish (US)
JournalAmerican Journal of Emergency Medicine
DOIs
StateAccepted/In press - Jul 1 2015

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Mucormycosis
Emergencies
Physicians
Immunocompromised Host
Hospital Emergency Service
Emergency Treatment
Fungi
Infection
Orbital Diseases
Antifungal Agents
Amphotericin B
Debridement
Necrosis
Therapeutics
Central Nervous System
Kidney
Lung
Skin

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Mucormycosis : What do emergency physicians need to know? / Long, Brit; Koyfman, Alex.

In: American Journal of Emergency Medicine, 01.07.2015.

Research output: Contribution to journalArticle

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