Multi-frequency PARACEST agents based on europium(III)DOTA-tetraamide ligands

Subha Viswanathan, S. James Ratnakar, Kayla N. Green, Zoltan Kovacs, Luis M. De Leónrodríguez, A. Dean Sherry

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Chemical Equation Presentation Colorful palette: A new class of highly selective Eu3+-based multi-frequency PARACEST agents is reported. The complexes can be tuned when administered simultaneously thereby allowing for the possibility of monitoring multiple biomarkers in parallel. PARACEST = paramagnetic chemical exchange saturation transfer.

Original languageEnglish (US)
Pages (from-to)9330-9333
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number49
DOIs
Publication statusPublished - Nov 23 2009

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Keywords

  • Europium
  • Imaging agents
  • Macrocycles
  • PARACEST
  • Saturation transfer

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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