Multi-modality tissue-mimicking phantom for thermal therapy

Mark McDonald; Shanna Lochhead; Rajiv Chopra; Michael J. Bronskill

doi:10.1088/0031-9155/49/13/001

Multi-modality tissue-mimicking phantom for thermal therapy

Mark McDonald, Shanna Lochhead, Rajiv Chopra, Michael J. Bronskill

Research output: Contribution to journal › Article

62 Scopus citations

Abstract

A tissue-mimicking phantom material has been developed for use with thermal therapy devices and techniques. This material has magnetic resonance properties (primarily T₂) which change drastically upon thermal coagulation, enabling its use for device characterization and treatment verification using simple T₂-weighted imaging techniques. The coagulation temperature of the phantom can be changed from 50-60 °C by adjusting the pH from 4.3 to 4.7. The energy absorption properties can be adjusted to match the acoustical and optical properties of tissues. T₂ relaxation measurements are provided as a function of temperature, along with T₂-weighted MR images to illustrate the visualization of heating patterns. A complete recipe for fabricating phantoms is provided.

Original language	English (US)
Pages (from-to)	2767-2778
Number of pages	12
Journal	Physics in Medicine and Biology
Volume	49
Issue number	13
DOIs	https://doi.org/10.1088/0031-9155/49/13/001
Publication status	Published - Jul 7 2004

Fingerprint

ASJC Scopus subject areas

Biomedical Engineering
Physics and Astronomy (miscellaneous)
Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

Cite this

McDonald, M., Lochhead, S., Chopra, R., & Bronskill, M. J. (2004). Multi-modality tissue-mimicking phantom for thermal therapy. Physics in Medicine and Biology, 49(13), 2767-2778. https://doi.org/10.1088/0031-9155/49/13/001

@article{dc7204c2f9774d84b7670bbe3a69638c,

title = "Multi-modality tissue-mimicking phantom for thermal therapy",

abstract = "A tissue-mimicking phantom material has been developed for use with thermal therapy devices and techniques. This material has magnetic resonance properties (primarily T2) which change drastically upon thermal coagulation, enabling its use for device characterization and treatment verification using simple T2-weighted imaging techniques. The coagulation temperature of the phantom can be changed from 50-60 °C by adjusting the pH from 4.3 to 4.7. The energy absorption properties can be adjusted to match the acoustical and optical properties of tissues. T2 relaxation measurements are provided as a function of temperature, along with T2-weighted MR images to illustrate the visualization of heating patterns. A complete recipe for fabricating phantoms is provided.",

author = "Mark McDonald and Shanna Lochhead and Rajiv Chopra and Bronskill, {Michael J.}",

year = "2004",

month = "7",

day = "7",

doi = "10.1088/0031-9155/49/13/001",

language = "English (US)",

volume = "49",

pages = "2767--2778",

journal = "Physics in Medicine and Biology",

issn = "0031-9155",

publisher = "IOP Publishing Ltd.",

number = "13",

}

TY - JOUR

T1 - Multi-modality tissue-mimicking phantom for thermal therapy

AU - McDonald, Mark

AU - Lochhead, Shanna

AU - Chopra, Rajiv

AU - Bronskill, Michael J.

PY - 2004/7/7

Y1 - 2004/7/7

N2 - A tissue-mimicking phantom material has been developed for use with thermal therapy devices and techniques. This material has magnetic resonance properties (primarily T2) which change drastically upon thermal coagulation, enabling its use for device characterization and treatment verification using simple T2-weighted imaging techniques. The coagulation temperature of the phantom can be changed from 50-60 °C by adjusting the pH from 4.3 to 4.7. The energy absorption properties can be adjusted to match the acoustical and optical properties of tissues. T2 relaxation measurements are provided as a function of temperature, along with T2-weighted MR images to illustrate the visualization of heating patterns. A complete recipe for fabricating phantoms is provided.

AB - A tissue-mimicking phantom material has been developed for use with thermal therapy devices and techniques. This material has magnetic resonance properties (primarily T2) which change drastically upon thermal coagulation, enabling its use for device characterization and treatment verification using simple T2-weighted imaging techniques. The coagulation temperature of the phantom can be changed from 50-60 °C by adjusting the pH from 4.3 to 4.7. The energy absorption properties can be adjusted to match the acoustical and optical properties of tissues. T2 relaxation measurements are provided as a function of temperature, along with T2-weighted MR images to illustrate the visualization of heating patterns. A complete recipe for fabricating phantoms is provided.

UR - http://www.scopus.com/inward/record.url?scp=3442896881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3442896881&partnerID=8YFLogxK

U2 - 10.1088/0031-9155/49/13/001

DO - 10.1088/0031-9155/49/13/001

M3 - Article

C2 - 15285246

AN - SCOPUS:3442896881

VL - 49

SP - 2767

EP - 2778

JO - Physics in Medicine and Biology

JF - Physics in Medicine and Biology

SN - 0031-9155

IS - 13

ER -

Access to Document

10.1088/0031-9155/49/13/001