Multicystic Dysplastic Kidney

April T. Bleich; Jodi S. Dashe

doi:10.1016/B978-0-323-44548-1.00015-2

Multicystic Dysplastic Kidney

April T. Bleich, Jodi S. Dashe

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

Original language	English (US)
Title of host publication	Obstetric Imaging
Subtitle of host publication	Fetal Diagnosis and Care: Second Edition
Publisher	Elsevier Inc.
Pages	58-62.e1
ISBN (Electronic)	9780323497367
ISBN (Print)	9780323445481
DOIs	https://doi.org/10.1016/B978-0-323-44548-1.00015-2
State	Published - 2018

Keywords

Compensatory hypertrophy
Corticomedullary differentiation
Renal dysplasia

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-323-44548-1.00015-2

Cite this

@inbook{19047501e4584c1e986f9cc21a8be139,

title = "Multicystic Dysplastic Kidney",

abstract = "Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.",

keywords = "Compensatory hypertrophy, Corticomedullary differentiation, Renal dysplasia",

author = "Bleich, {April T.} and Dashe, {Jodi S.}",

year = "2018",

doi = "10.1016/B978-0-323-44548-1.00015-2",

language = "English (US)",

isbn = "9780323445481",

pages = "58--62.e1",

booktitle = "Obstetric Imaging",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Multicystic Dysplastic Kidney

AU - Bleich, April T.

AU - Dashe, Jodi S.

PY - 2018

Y1 - 2018

N2 - Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

AB - Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

KW - Compensatory hypertrophy

KW - Corticomedullary differentiation

KW - Renal dysplasia

UR - http://www.scopus.com/inward/record.url?scp=85054669450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054669450&partnerID=8YFLogxK

U2 - 10.1016/B978-0-323-44548-1.00015-2

DO - 10.1016/B978-0-323-44548-1.00015-2

M3 - Chapter

AN - SCOPUS:85054669450

SN - 9780323445481

SP - 58-62.e1

BT - Obstetric Imaging

PB - Elsevier Inc.

ER -

Multicystic Dysplastic Kidney

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this