Multicystic dysplastic kidney

April T. Bleich, Jodi S. Dashe

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

Original languageEnglish (US)
Title of host publicationObstetric Imaging
Subtitle of host publicationFetal Diagnosis and Care, 2nd Edition
PublisherElsevier
Pages58-62.e1
ISBN (Electronic)9780323445481
DOIs
StatePublished - Jan 1 2017

Keywords

  • Compensatory hypertrophy
  • Corticomedullary differentiation
  • Renal dysplasia

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Bleich, A. T., & Dashe, J. S. (2017). Multicystic dysplastic kidney. In Obstetric Imaging: Fetal Diagnosis and Care, 2nd Edition (pp. 58-62.e1). Elsevier. https://doi.org/10.1016/B978-0-323-44548-1.00015-2