Multimodal imaging in the diagnosis and management of ophthalmia nodosa

Noy Ashkenazy, Philip J. Rosenfeld, Janet L. Davis

Research output: Contribution to journalArticlepeer-review


Purpose: Ophthalmia nodosa (ON) is a rare but important disease describing ocular inflammation caused by injury from insect hairs (“setae”). Type V ON occurs when there is vitreoretinal involvement. Treatment with systemic steroids are first-line, but vitrectomy is indicated in resistant cases. The purpose of this study was to illustrate how multimodal imaging can facilitate diagnosis and management of ON. Observations: This is a single retrospective case report of a patient who presented to Bascom Palmer Eye Institute with Type V ON. Multimodal imaging in a patient with Type V ON was illustrated. A moth seta was localized to the anterior vitreous cavity. Intraocular inflammation responded to 2 weeks of high-dose oral prednisone. Conclusions and Importance: Multimodal imaging may guide diagnosis and management of ON by documenting baseline features of ON and facilitating comparison at follow up visits. This allows for safe non-surgical management of Type V ON. Long-term follow up would be necessary to determine whether subsequent surgical intervention was needed in this case.

Original languageEnglish (US)
Article number101692
JournalAmerican Journal of Ophthalmology Case Reports
StatePublished - Dec 2022
Externally publishedYes


  • Corticosteroids
  • Multimodal imaging
  • Ophthalmia nodosa
  • Uveitis
  • Vitreoretinal surgery

ASJC Scopus subject areas

  • Ophthalmology


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