Multimodality assessment of upper airway obstruction in children with persistent obstructive sleep apnea after adenotonsillectomy

Christopher Clark, Seckin O. Ulualp

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives/Hypothesis: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). Study Design: Retrospective chart review. Material and Methods: The medical records of children who underwent DISE and cine MRI were reviewed. Data pertaining to demographics, past medical history, body mass index, polysomnography, findings of DISE, and cine MRI were obtained. Results: Fifteen children (11 boys, 4 girls; age range, 7-18 years) were identified. Comorbid conditions were Down syndrome in nine patients, cerebral palsy in one, attention deficit hyperactivity disorder in two, and asthma in three. Severity of OSA was moderate in five, and severe in 10. DISE and cine MRI showed the same UAO site in 10 patients: a single site (tongue) in nine and multiple sites (tongue and oropharynx/lateral walls) in one. DISE showed additional UAO sites undetected by cine MRI in three patients. Cine MRI showed additional UAO sites undetected by DISE in one patient. DISE and cine MRI showed different sites of obstruction in one patient. Conclusions: Cine MRI and DISE documented single and multiple sites of UAO in children with persistent OSA after AT. Cine MRI and DISE findings were similar in the majority of the children. Assessment of the sensitivity and specificity of cine MRI and DISE in detecting sites of UAO merits further investigation.

Original languageEnglish (US)
JournalLaryngoscope
DOIs
StateAccepted/In press - 2016

Fingerprint

Cine Magnetic Resonance Imaging
Obstructive Sleep Apnea
Airway Obstruction
Endoscopy
Sleep
Pharmaceutical Preparations
Tongue
Oropharynx
Polysomnography
Cerebral Palsy
Attention Deficit Disorder with Hyperactivity
Down Syndrome
Medical Records
Body Mass Index
Asthma
Retrospective Studies
Demography

Keywords

  • Children
  • Drug-induced sleep endoscopy
  • Magnetic resonance imaging
  • Obstructive sleep apnea
  • Tonsillectomy and adenoidectomy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

@article{bea6e970f28b4df78a158209d654833a,
title = "Multimodality assessment of upper airway obstruction in children with persistent obstructive sleep apnea after adenotonsillectomy",
abstract = "Objectives/Hypothesis: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). Study Design: Retrospective chart review. Material and Methods: The medical records of children who underwent DISE and cine MRI were reviewed. Data pertaining to demographics, past medical history, body mass index, polysomnography, findings of DISE, and cine MRI were obtained. Results: Fifteen children (11 boys, 4 girls; age range, 7-18 years) were identified. Comorbid conditions were Down syndrome in nine patients, cerebral palsy in one, attention deficit hyperactivity disorder in two, and asthma in three. Severity of OSA was moderate in five, and severe in 10. DISE and cine MRI showed the same UAO site in 10 patients: a single site (tongue) in nine and multiple sites (tongue and oropharynx/lateral walls) in one. DISE showed additional UAO sites undetected by cine MRI in three patients. Cine MRI showed additional UAO sites undetected by DISE in one patient. DISE and cine MRI showed different sites of obstruction in one patient. Conclusions: Cine MRI and DISE documented single and multiple sites of UAO in children with persistent OSA after AT. Cine MRI and DISE findings were similar in the majority of the children. Assessment of the sensitivity and specificity of cine MRI and DISE in detecting sites of UAO merits further investigation.",
keywords = "Children, Drug-induced sleep endoscopy, Magnetic resonance imaging, Obstructive sleep apnea, Tonsillectomy and adenoidectomy",
author = "Christopher Clark and Ulualp, {Seckin O.}",
year = "2016",
doi = "10.1002/lary.26174",
language = "English (US)",
journal = "Laryngoscope",
issn = "0023-852X",
publisher = "John Wiley and Sons Inc.",

}

TY - JOUR

T1 - Multimodality assessment of upper airway obstruction in children with persistent obstructive sleep apnea after adenotonsillectomy

AU - Clark, Christopher

AU - Ulualp, Seckin O.

PY - 2016

Y1 - 2016

N2 - Objectives/Hypothesis: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). Study Design: Retrospective chart review. Material and Methods: The medical records of children who underwent DISE and cine MRI were reviewed. Data pertaining to demographics, past medical history, body mass index, polysomnography, findings of DISE, and cine MRI were obtained. Results: Fifteen children (11 boys, 4 girls; age range, 7-18 years) were identified. Comorbid conditions were Down syndrome in nine patients, cerebral palsy in one, attention deficit hyperactivity disorder in two, and asthma in three. Severity of OSA was moderate in five, and severe in 10. DISE and cine MRI showed the same UAO site in 10 patients: a single site (tongue) in nine and multiple sites (tongue and oropharynx/lateral walls) in one. DISE showed additional UAO sites undetected by cine MRI in three patients. Cine MRI showed additional UAO sites undetected by DISE in one patient. DISE and cine MRI showed different sites of obstruction in one patient. Conclusions: Cine MRI and DISE documented single and multiple sites of UAO in children with persistent OSA after AT. Cine MRI and DISE findings were similar in the majority of the children. Assessment of the sensitivity and specificity of cine MRI and DISE in detecting sites of UAO merits further investigation.

AB - Objectives/Hypothesis: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). Study Design: Retrospective chart review. Material and Methods: The medical records of children who underwent DISE and cine MRI were reviewed. Data pertaining to demographics, past medical history, body mass index, polysomnography, findings of DISE, and cine MRI were obtained. Results: Fifteen children (11 boys, 4 girls; age range, 7-18 years) were identified. Comorbid conditions were Down syndrome in nine patients, cerebral palsy in one, attention deficit hyperactivity disorder in two, and asthma in three. Severity of OSA was moderate in five, and severe in 10. DISE and cine MRI showed the same UAO site in 10 patients: a single site (tongue) in nine and multiple sites (tongue and oropharynx/lateral walls) in one. DISE showed additional UAO sites undetected by cine MRI in three patients. Cine MRI showed additional UAO sites undetected by DISE in one patient. DISE and cine MRI showed different sites of obstruction in one patient. Conclusions: Cine MRI and DISE documented single and multiple sites of UAO in children with persistent OSA after AT. Cine MRI and DISE findings were similar in the majority of the children. Assessment of the sensitivity and specificity of cine MRI and DISE in detecting sites of UAO merits further investigation.

KW - Children

KW - Drug-induced sleep endoscopy

KW - Magnetic resonance imaging

KW - Obstructive sleep apnea

KW - Tonsillectomy and adenoidectomy

UR - http://www.scopus.com/inward/record.url?scp=84978718191&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978718191&partnerID=8YFLogxK

U2 - 10.1002/lary.26174

DO - 10.1002/lary.26174

M3 - Article

C2 - 27411973

AN - SCOPUS:84978718191

JO - Laryngoscope

JF - Laryngoscope

SN - 0023-852X

ER -