TY - JOUR
T1 - Multinucleate cell angiohistiocytoma
T2 - A case report and review of the literature
AU - Applebaum, Danielle S.
AU - Shuja, Fareesa
AU - Hicks, Lindsey
AU - Cockerell, Clay
AU - Hsu, Sylvia
PY - 2014
Y1 - 2014
N2 - Multinucleate cell angiohistiocytoma (MCAH) is a rare, benign vascular proliferation. Fewer than 80 cases have been reported to date, which may relate to under-recognition of this entity. Lesions are commonly asymptomatic and appear as erythematous to violaceous papules on the lower extremities and dorsal hands of middle-aged to elderly women. The characteristic histopathologic and immunohistochemical features of MCAH are essential for definitive diagnosis of MCAH. Multinucleate cell angiohistiocytoma follows a slowly progressive course, although spontaneous regression has been reported in rare cases. We present a case of MCAH to increase awareness and elucidate the characteristic clinical and histopathologic features of this disorder.
AB - Multinucleate cell angiohistiocytoma (MCAH) is a rare, benign vascular proliferation. Fewer than 80 cases have been reported to date, which may relate to under-recognition of this entity. Lesions are commonly asymptomatic and appear as erythematous to violaceous papules on the lower extremities and dorsal hands of middle-aged to elderly women. The characteristic histopathologic and immunohistochemical features of MCAH are essential for definitive diagnosis of MCAH. Multinucleate cell angiohistiocytoma follows a slowly progressive course, although spontaneous regression has been reported in rare cases. We present a case of MCAH to increase awareness and elucidate the characteristic clinical and histopathologic features of this disorder.
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M3 - Article
C2 - 24852770
AN - SCOPUS:84901198773
SN - 1087-2108
VL - 20
JO - Dermatology online journal
JF - Dermatology online journal
IS - 5
M1 - 4
ER -