Multiple sclerosis

Kathleen Hawker, Elliot Frohman

Research output: Contribution to journalArticle

Abstract

Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.

Original languageEnglish (US)
Pages (from-to)201-226
Number of pages26
JournalPrimary Care - Clinics in Office Practice
Volume31
Issue number1
DOIs
StatePublished - Mar 2004

Fingerprint

Multiple Sclerosis
Early Diagnosis
Myelin Sheath
Neurologic Manifestations
Autoimmune Diseases
Axons
Spinal Cord
Central Nervous System
Inflammation
Recurrence
Brain
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Multiple sclerosis. / Hawker, Kathleen; Frohman, Elliot.

In: Primary Care - Clinics in Office Practice, Vol. 31, No. 1, 03.2004, p. 201-226.

Research output: Contribution to journalArticle

Hawker, Kathleen ; Frohman, Elliot. / Multiple sclerosis. In: Primary Care - Clinics in Office Practice. 2004 ; Vol. 31, No. 1. pp. 201-226.
@article{68bdbbfbf1e54475bb5e95750ca7b9d4,
title = "Multiple sclerosis",
abstract = "Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.",
author = "Kathleen Hawker and Elliot Frohman",
year = "2004",
month = "3",
doi = "10.1016/S0095-4543(03)00123-4",
language = "English (US)",
volume = "31",
pages = "201--226",
journal = "Primary Care - Clinics in Office Practice",
issn = "0095-4543",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Multiple sclerosis

AU - Hawker, Kathleen

AU - Frohman, Elliot

PY - 2004/3

Y1 - 2004/3

N2 - Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.

AB - Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.

UR - http://www.scopus.com/inward/record.url?scp=2142818545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2142818545&partnerID=8YFLogxK

U2 - 10.1016/S0095-4543(03)00123-4

DO - 10.1016/S0095-4543(03)00123-4

M3 - Article

C2 - 15110166

AN - SCOPUS:2142818545

VL - 31

SP - 201

EP - 226

JO - Primary Care - Clinics in Office Practice

JF - Primary Care - Clinics in Office Practice

SN - 0095-4543

IS - 1

ER -