TY - JOUR
T1 - Multiple sclerosis
AU - Hawker, Kathleen
AU - Frohman, Elliot
PY - 2004/3
Y1 - 2004/3
N2 - Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.
AB - Multiple sclerosis is the most common disabling disease of young people, affecting 350,000 to 500,000 individuals in the United States. Multiple sclerosis is an autoimmune disease, causing inflammation, myelin breakdown, and loss of axons in the central nervous system. Depending on the location of the lesion within the brain or spinal cord, it may present with a variety of neurologic symptoms. Symptoms may relapse and remit; however, typically healing is incomplete after an attack, producing permanent disability. Early treatment of the disease may reduce the development of disability. Early diagnosis is a crucial first step in identifying patients with the disease. Family practitioners, as the first line of contact for most patients, play a pivotal role in facilitating early diagnosis and early treatment.
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U2 - 10.1016/S0095-4543(03)00123-4
DO - 10.1016/S0095-4543(03)00123-4
M3 - Review article
C2 - 15110166
AN - SCOPUS:2142818545
SN - 0095-4543
VL - 31
SP - 201
EP - 226
JO - Primary Care - Clinics in Office Practice
JF - Primary Care - Clinics in Office Practice
IS - 1
ER -