Abstract
Four of 10 patients who were enrolled on protocols of high-dose immunosuppression with peripheral blood stem cell rescue for MS experienced neurologic worsening while receiving recombinant human granulocyte colony- stimulating factor. There was improvement when methylprednisolone was given to three of the patients, but one patient died of respiratory failure. The mechanism of the neurologic worsening is uncertain.
Original language | English (US) |
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Pages (from-to) | 2147-2150 |
Number of pages | 4 |
Journal | Neurology |
Volume | 54 |
Issue number | 11 |
DOIs | |
State | Published - Jun 13 2000 |
Keywords
- Granulocyte colony-stimulating factor
- Immunosuppression
- MS
- Stem cell transplantation
ASJC Scopus subject areas
- Clinical Neurology