Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

Medicine & Life Sciences

• Hydroxymethylglutaryl CoA Reductases 96%
• Terpenes 85%
• Mevalonic Acid 75%
• Oxidoreductases 64%
• 3-hydroxy-3-methylglutaryl-coenzyme A 55%
• mevastatin 46%
• Growth 35%
• Cholesterol 20%
• Sterols 16%
• Enzymes 15%
• LDL Lipoproteins 14%
• Cultured Cells 11%
• Cell Culture Techniques 10%

Chemical Compounds

• Mevalonate 100%
• Isoprenoid 90%
• Coenzyme A 65%
• Pharmacological Metabolism 40%
• Mammalian Cell 36%
• Cholesterol 31%
• Sterol 19%
• Plasma 10%