Mutations in human 11β-hydroxylase genes: 11β-hydroxylase deficiency in Jews of Morocco and corticosterone methyl-oxidase II deficiency in Jews of Iran

Medicine & Life Sciences

• corticosterone methyl oxidase II 100%
• Steroid 11-beta-Hydroxylase 76%
• corticosterone methyl oxidase I 69%
• Jews 67%
• Morocco 65%
• Mixed Function Oxygenases 53%
• Cytochrome P-450 CYP11B2 47%
• Iran 46%
• Mutation 26%
• Codon 23%
• Exons 19%
• Genes 19%
• 18-Hydroxylase deficiency 16%
• Aldosterone 16%
• Arginine 14%
• Androgens 14%
• Hydrocortisone 14%
• 18-Hydroxycorticosterone 13%
• Steroids 11%
• Wasting Syndrome 11%
• Parturition 11%
• Virilism 11%
• Chromosomes, Human, Pair 22 10%
• Desoxycorticosterone 10%
• Mineralocorticoids 10%
• Valine 9%
• Israel 8%
• Heme 8%
• Histidine 8%
• Missense Mutation 8%
• Alanine 8%
• Isoenzymes 7%
• Point Mutation 7%
• Cytochrome P-450 Enzyme System 7%
• Oxidoreductases 7%
• Salts 7%
• Alleles 5%
• Hypertension 5%

Chemical Compounds

• Corticosterone 66%
• Mutation 40%
• Biosynthesis 22%
• Aldosterone 19%
• Steroid 18%
• Cortisol 17%
• Androgen 17%
• Arginine 13%
• 18-Hydroxycorticosterone 12%
• Mineralocorticoid 10%
• Substitution Reaction 8%
• Valine 7%
• Alanine 6%
• Histidine 6%
• Heme 6%
• Cytochrome 5%
• Enzyme Activity 5%
• Reduction 3%