Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions

Medicine & Life Sciences

• Hypotrichosis, Localized, Autosomal Recessive 1 100%
• Monilethrix 83%
• Desmogleins 71%
• Scalp 45%
• Mutation 25%
• Missense Mutation 23%
• Desmosomal Cadherins 18%
• Genes 18%
• Hair Follicle 13%
• Pruritus 11%
• Epidermis 11%
• Binding Sites 8%
• Extremities 8%
• Calcium 7%

Chemical Compounds

• Mutation 37%
• Disorder 15%
• Shaft 12%