Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells

T. M. Beyers, W. C. Lai, R. W. Read, S. P. Pakes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Results of competitive binding studies with radiolabeled and unlabeled Mycoplasma pulmonis and rat tracheal explant cultures indicated no effect of trypsin treatment on the ability of M. pulmonis to bind to explants. A trypsin-resistant 46-kDa membrane protein, which binds isolated rat tracheal epithelial cells in culture, was purified and used to produce specific antibodies that block adhesion of mycoplasmas to tracheal explants. These results suggest that M. pulmonis adheres to rat tracheal epithelium via a trypsin-resistant 46-kDa protein.

Original languageEnglish (US)
Pages (from-to)573-578
Number of pages6
JournalLaboratory Animal Science
Volume44
Issue number6
StatePublished - 1994

Fingerprint

Mycoplasma pulmonis
Trypsin
trypsin
Rats
explants
epithelial cells
Epithelial Cells
rats
Proteins
Competitive Binding
proteins
Mycoplasma
membrane proteins
adhesion
Membrane Proteins
cell culture
epithelium
Adhesion
Epithelium
Cell Culture Techniques

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Beyers, T. M., Lai, W. C., Read, R. W., & Pakes, S. P. (1994). Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells. Laboratory Animal Science, 44(6), 573-578.

Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells. / Beyers, T. M.; Lai, W. C.; Read, R. W.; Pakes, S. P.

In: Laboratory Animal Science, Vol. 44, No. 6, 1994, p. 573-578.

Research output: Contribution to journalArticle

Beyers, TM, Lai, WC, Read, RW & Pakes, SP 1994, 'Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells', Laboratory Animal Science, vol. 44, no. 6, pp. 573-578.
Beyers, T. M. ; Lai, W. C. ; Read, R. W. ; Pakes, S. P. / Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells. In: Laboratory Animal Science. 1994 ; Vol. 44, No. 6. pp. 573-578.
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