Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells

T. M. Beyers, W. C. Lai, R. W. Read, S. P. Pakes

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Results of competitive binding studies with radiolabeled and unlabeled Mycoplasma pulmonis and rat tracheal explant cultures indicated no effect of trypsin treatment on the ability of M. pulmonis to bind to explants. A trypsin-resistant 46-kDa membrane protein, which binds isolated rat tracheal epithelial cells in culture, was purified and used to produce specific antibodies that block adhesion of mycoplasmas to tracheal explants. These results suggest that M. pulmonis adheres to rat tracheal epithelium via a trypsin-resistant 46-kDa protein.

Original languageEnglish (US)
Pages (from-to)573-578
Number of pages6
JournalLaboratory animal science
Volume44
Issue number6
StatePublished - Dec 1 1994

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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    Beyers, T. M., Lai, W. C., Read, R. W., & Pakes, S. P. (1994). Mycoplasma pulmonis 46-kDa trypsin-resistant protein adheres to rat tracheal epithelial cells. Laboratory animal science, 44(6), 573-578.