Myxoid chondrosarcoma of the sphenoid sinus and chondromyxoid fibroma of the iliac bone: Cytomorphological findings of two distinct and uncommon myxoid lesions

Luis E. De Las Casas, Harsharan K. Singh, Bradford E. Halliday, Fushen Xu, Paul H. Strausbauch, Jan F. Silverman

Research output: Contribution to journalArticlepeer-review

Abstract

Myxoid chondrosarcoma (MCS) and chondromyxoid fibroma (CMF) are two uncommon myxoid cartilaginous neoplasms with distinct cytologic features, histologic patterns, and immunoprofiles. Because these neoplasms have characteristic biological behaviors and management, their correct diagnosis is crucial to avoid debilitating and unnecessary surgical procedures. We report the imprint cytology (IC) preparation findings along with the differential diagnosis in one case each of myxoid chondrosarcoma and chondromyxoid fibroma of the splenoid sinus and iliac bone, respectively. The two great mimickers for these neoplasms, chordoma and chondrosarcoma, represent difficult diagnostic challenges, especially when MCS and CMF occur in unusual locations. IC in conjunction with the clinical and radiologic findings can provide a rapid preliminary intraoperative diagnostic interpretation which can aid in planning the immediate surgical management, as well as guide specific tissue triage for key ancillary studies such as electron microscopy and cytogenetic analyses. To the best of our knowledge, there have been no cytologic reports of MCS of the sphenoid sinus and CMF of the iliac bone. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalDiagnostic cytopathology
Volume22
Issue number6
DOIs
StatePublished - Jun 2000
Externally publishedYes

Keywords

  • Chondromyxoid fibroma
  • Imprint cytology
  • Myxoid chondrosarcoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Fingerprint

Dive into the research topics of 'Myxoid chondrosarcoma of the sphenoid sinus and chondromyxoid fibroma of the iliac bone: Cytomorphological findings of two distinct and uncommon myxoid lesions'. Together they form a unique fingerprint.

Cite this