N -acylsulfonamide assisted tandem C-H olefination/annulation: Synthesis of isoindolinones

Chen Zhu, J R Falck

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Abstract

A tandem C-H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.(Figure Presented)

Original languageEnglish (US)
Pages (from-to)1214-1217
Number of pages4
JournalOrganic Letters
Volume13
Issue number5
DOIs
Publication statusPublished - Mar 4 2011

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ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

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