Nanofabricated sensing electrodes in a batteryless endoluminal sensing telemeter for diagnosis of Gastroesophageal Reflux Disease (GERD)

Lun Chen Hsu, Wen Ding Huang, Shou Jiang Tang, Stuart Spechler, H. F. Tibbals, J. C. Chiao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Gastroesophageal reflux disease (GERD) is recognized the primary risk factor associated with esophageal cancers. Therefore, monitoring GERD symptoms accurately is important for early diagnosis of such cancers. In this work, interdigitated impedance sensing electrodes and nanofabricated IrOx-based pH sensing electrodes were made on the flexible substrates that can be easily embedded into an implantable device. The dual sensor electrodes were integrated into a batteryless wireless capsule packaged with biocompatible material for implant applications. The proposed sensing system has been tested with stimulated solutions of different pH values recording modulated sensor data in terms of frequency shifts to verify its performance. The experimental results showed that the impedance electrodes responded to ion content variations and the pH electrodes identified the pH values of various pH solutions. Our sensing system has demonstrated the ability to detect gastroesophageal reflux activities more accurately, which could help doctors to provide precise treatment methods, consequentially lowering the risks of esophageal cancer development.

Original languageEnglish (US)
Title of host publicationProceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010
Pages65-66
Number of pages2
StatePublished - Aug 4 2010
Event1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010 - Houston, TX, United States
Duration: Feb 7 2010Feb 10 2010

Publication series

NameProceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010

Other

Other1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010
CountryUnited States
CityHouston, TX
Period2/7/102/10/10

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ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine(all)

Cite this

Hsu, L. C., Huang, W. D., Tang, S. J., Spechler, S., Tibbals, H. F., & Chiao, J. C. (2010). Nanofabricated sensing electrodes in a batteryless endoluminal sensing telemeter for diagnosis of Gastroesophageal Reflux Disease (GERD). In Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010 (pp. 65-66). (Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010).