Nanotechnology Approaches to Improving Cancer Immunotherapy

C. Tilden Hagan, Yusra B. Medik, Andrew Z. Wang

Research output: Chapter in Book/Report/Conference proceedingChapter

24 Scopus citations

Abstract

Cancer immunotherapy is a powerful, growing treatment approach to cancer that can be combined with chemotherapy, radiotherapy, and oncosurgery. Modulating the immune system to enhance anticancer response by several strategies has yielded improved cancer survival. Despite this progress, the success rate for immunotherapy has been below expectations due to unpredictable efficacy and off-target side effects from systemic dosing. Nanotechnology offers numerous different materials and targeting properties to overcome many of these challenges in immunotherapy. In this chapter, we review current immunotherapy and its challenges as well as the latest nanotechnology applications in cancer immunotherapy.

Original languageEnglish (US)
Title of host publicationAdvances in Cancer Research
EditorsAnn-Marie Broome
PublisherAcademic Press Inc.
Pages35-56
Number of pages22
ISBN (Print)9780128141694
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Publication series

NameAdvances in Cancer Research
Volume139
ISSN (Print)0065-230X
ISSN (Electronic)2162-5557

Keywords

  • Cancer immunotherapy
  • Immune resistance
  • Nanoparticles
  • Nanotechnology
  • Tumor microenvironment

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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