Negative emotion interference during a synonym matching task in pediatric bipolar disorder with and without attention deficit hyperactivity disorder

Alessandra M. Passarotti, Jacklynn M. Fitzgerald, John A. Sweeney, Mani N. Pavuluri

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This study examined whether processing of emotional words impairs cognitive performance in acutely ill patients with pediatric bipolar disorder (PBD), with or without comorbid attention-deficit hyperactivity disorder (ADHD), relative to healthy controls (HC). Forty youths with PBD without ADHD, 20 youths with PBD and ADHD, and 29 HC (mean age = 12.97 ± 3.13) performed a Synonym Matching task, where they decided which of two probe words was the synonym of a target word. The three words presented on each trial all had the same emotional valence, which could be negative, positive, or neutral. Relative to HC both PBD groups exhibited worse accuracy for emotional words relative to neutral ones. This effect was greater with negative words and observed regardless of whether PBD patients had comorbid ADHD. In the PBD group without ADHD, manic symptoms correlated negatively with accuracy for negative words, and positively with reaction time (RT) for all word types. Our findings suggest a greater disruptive effect of emotional valence in both PBD groups relative to HC, reflecting the adverse effect of altered emotion processing on cognitive function in PBD. Future studies including an ADHD group will help clarify how ADHD symptoms may affect emotional interference independently of PBD.

Original languageEnglish (US)
Pages (from-to)601-612
Number of pages12
JournalJournal of the International Neuropsychological Society
Volume19
Issue number5
DOIs
StatePublished - May 2013

Fingerprint

ADHD
Attention Deficit Disorder with Hyperactivity
Bipolar Disorder
interference
Emotions
emotion
Pediatrics
Group
Word Processing
Synonyms
Interference
Emotion
Attention Deficit Hyperactivity Disorder
Cognition
performance

Keywords

  • ADHD
  • Attention bias
  • Bipolar
  • Emotion
  • Interference
  • Youths

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Clinical Psychology
  • Neuroscience(all)
  • Language and Linguistics
  • Linguistics and Language

Cite this

Negative emotion interference during a synonym matching task in pediatric bipolar disorder with and without attention deficit hyperactivity disorder. / Passarotti, Alessandra M.; Fitzgerald, Jacklynn M.; Sweeney, John A.; Pavuluri, Mani N.

In: Journal of the International Neuropsychological Society, Vol. 19, No. 5, 05.2013, p. 601-612.

Research output: Contribution to journalArticle

@article{a2302e761a244189bbcba815d56e7a3b,
title = "Negative emotion interference during a synonym matching task in pediatric bipolar disorder with and without attention deficit hyperactivity disorder",
abstract = "This study examined whether processing of emotional words impairs cognitive performance in acutely ill patients with pediatric bipolar disorder (PBD), with or without comorbid attention-deficit hyperactivity disorder (ADHD), relative to healthy controls (HC). Forty youths with PBD without ADHD, 20 youths with PBD and ADHD, and 29 HC (mean age = 12.97 ± 3.13) performed a Synonym Matching task, where they decided which of two probe words was the synonym of a target word. The three words presented on each trial all had the same emotional valence, which could be negative, positive, or neutral. Relative to HC both PBD groups exhibited worse accuracy for emotional words relative to neutral ones. This effect was greater with negative words and observed regardless of whether PBD patients had comorbid ADHD. In the PBD group without ADHD, manic symptoms correlated negatively with accuracy for negative words, and positively with reaction time (RT) for all word types. Our findings suggest a greater disruptive effect of emotional valence in both PBD groups relative to HC, reflecting the adverse effect of altered emotion processing on cognitive function in PBD. Future studies including an ADHD group will help clarify how ADHD symptoms may affect emotional interference independently of PBD.",
keywords = "ADHD, Attention bias, Bipolar, Emotion, Interference, Youths",
author = "Passarotti, {Alessandra M.} and Fitzgerald, {Jacklynn M.} and Sweeney, {John A.} and Pavuluri, {Mani N.}",
year = "2013",
month = "5",
doi = "10.1017/S135561771300012X",
language = "English (US)",
volume = "19",
pages = "601--612",
journal = "Journal of the International Neuropsychological Society",
issn = "1355-6177",
publisher = "Cambridge University Press",
number = "5",

}

TY - JOUR

T1 - Negative emotion interference during a synonym matching task in pediatric bipolar disorder with and without attention deficit hyperactivity disorder

AU - Passarotti, Alessandra M.

AU - Fitzgerald, Jacklynn M.

AU - Sweeney, John A.

AU - Pavuluri, Mani N.

PY - 2013/5

Y1 - 2013/5

N2 - This study examined whether processing of emotional words impairs cognitive performance in acutely ill patients with pediatric bipolar disorder (PBD), with or without comorbid attention-deficit hyperactivity disorder (ADHD), relative to healthy controls (HC). Forty youths with PBD without ADHD, 20 youths with PBD and ADHD, and 29 HC (mean age = 12.97 ± 3.13) performed a Synonym Matching task, where they decided which of two probe words was the synonym of a target word. The three words presented on each trial all had the same emotional valence, which could be negative, positive, or neutral. Relative to HC both PBD groups exhibited worse accuracy for emotional words relative to neutral ones. This effect was greater with negative words and observed regardless of whether PBD patients had comorbid ADHD. In the PBD group without ADHD, manic symptoms correlated negatively with accuracy for negative words, and positively with reaction time (RT) for all word types. Our findings suggest a greater disruptive effect of emotional valence in both PBD groups relative to HC, reflecting the adverse effect of altered emotion processing on cognitive function in PBD. Future studies including an ADHD group will help clarify how ADHD symptoms may affect emotional interference independently of PBD.

AB - This study examined whether processing of emotional words impairs cognitive performance in acutely ill patients with pediatric bipolar disorder (PBD), with or without comorbid attention-deficit hyperactivity disorder (ADHD), relative to healthy controls (HC). Forty youths with PBD without ADHD, 20 youths with PBD and ADHD, and 29 HC (mean age = 12.97 ± 3.13) performed a Synonym Matching task, where they decided which of two probe words was the synonym of a target word. The three words presented on each trial all had the same emotional valence, which could be negative, positive, or neutral. Relative to HC both PBD groups exhibited worse accuracy for emotional words relative to neutral ones. This effect was greater with negative words and observed regardless of whether PBD patients had comorbid ADHD. In the PBD group without ADHD, manic symptoms correlated negatively with accuracy for negative words, and positively with reaction time (RT) for all word types. Our findings suggest a greater disruptive effect of emotional valence in both PBD groups relative to HC, reflecting the adverse effect of altered emotion processing on cognitive function in PBD. Future studies including an ADHD group will help clarify how ADHD symptoms may affect emotional interference independently of PBD.

KW - ADHD

KW - Attention bias

KW - Bipolar

KW - Emotion

KW - Interference

KW - Youths

UR - http://www.scopus.com/inward/record.url?scp=84877145626&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877145626&partnerID=8YFLogxK

U2 - 10.1017/S135561771300012X

DO - 10.1017/S135561771300012X

M3 - Article

VL - 19

SP - 601

EP - 612

JO - Journal of the International Neuropsychological Society

JF - Journal of the International Neuropsychological Society

SN - 1355-6177

IS - 5

ER -