TY - JOUR
T1 - Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion
T2 - A single institutional experience
AU - Adogwa, Owoicho
AU - Fatemi, Parastou
AU - Perez, Edgar
AU - Moreno, Jessica
AU - Gazcon, Gustavo Chagoya
AU - Gokaslan, Ziya L.
AU - Cheng, Joseph
AU - Gottfried, Oren
AU - Bagley, Carlos A.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Background context Wound dehiscence and surgical site infections (SSIs) can have a profound impact on patients as they often require hospital readmission, additional surgical interventions, lengthy intravenous antibiotic administration, and delayed rehabilitation. Negative pressure wound therapy (NPWT) exposes the wound site to negative pressure, resulting in the improvement of blood supply, removal of excess fluid, and stimulation of cellular proliferation of granulation tissue.Study design Retrospective study.Patient sample One hundred sixty patients undergoing long-segment thoracolumbar spine fusions were included in this study.Outcome measures Postoperative incidence of wound infection and dehiscence.Methods All adult patients undergoing thoracolumbar fusion for spinal deformity over a 6-year period at Duke University Medical Center by the senior author (CB) were included in this study. In 2012, a categorical change was made by the senior author (CB) that included the postoperative routine use of incisional NPWT devices after primary wound closure in all long-segment spine fusions. Before 2012, NPWT was not used. After primary wound closure, a negative pressure device is contoured to the size of the incision and placed over the incision site for 3 postoperative days. We retrospectively review the first 46 cases in which NPWT was used and compared them with the immediately preceding 114 cases to assess the incidence of wound infection and dehiscence.Results One hundred sixty (NPWT: 46 cases, non-NPWT: 114 cases) long-segment thoracolumbar spine fusions were performed for deformity correction. Baseline characteristics were similar between both cohorts. Compared with the non-NPWT cohort, a 50% decrease in the incidence of wound dehiscence was observed in the NPWT patient cohort (6.38% vs. 12.28%, p=.02). Similarly, compared with the non-NPWT cohort, the incidence of postoperative SSIs was significantly decreased in the NPWT cohort (10.63% vs. 14.91%, p=.04).Conclusions Routine use of incisional NPWT was associated with a significant reduction in the incidence of postoperative wound infection and dehiscence.
AB - Background context Wound dehiscence and surgical site infections (SSIs) can have a profound impact on patients as they often require hospital readmission, additional surgical interventions, lengthy intravenous antibiotic administration, and delayed rehabilitation. Negative pressure wound therapy (NPWT) exposes the wound site to negative pressure, resulting in the improvement of blood supply, removal of excess fluid, and stimulation of cellular proliferation of granulation tissue.Study design Retrospective study.Patient sample One hundred sixty patients undergoing long-segment thoracolumbar spine fusions were included in this study.Outcome measures Postoperative incidence of wound infection and dehiscence.Methods All adult patients undergoing thoracolumbar fusion for spinal deformity over a 6-year period at Duke University Medical Center by the senior author (CB) were included in this study. In 2012, a categorical change was made by the senior author (CB) that included the postoperative routine use of incisional NPWT devices after primary wound closure in all long-segment spine fusions. Before 2012, NPWT was not used. After primary wound closure, a negative pressure device is contoured to the size of the incision and placed over the incision site for 3 postoperative days. We retrospectively review the first 46 cases in which NPWT was used and compared them with the immediately preceding 114 cases to assess the incidence of wound infection and dehiscence.Results One hundred sixty (NPWT: 46 cases, non-NPWT: 114 cases) long-segment thoracolumbar spine fusions were performed for deformity correction. Baseline characteristics were similar between both cohorts. Compared with the non-NPWT cohort, a 50% decrease in the incidence of wound dehiscence was observed in the NPWT patient cohort (6.38% vs. 12.28%, p=.02). Similarly, compared with the non-NPWT cohort, the incidence of postoperative SSIs was significantly decreased in the NPWT cohort (10.63% vs. 14.91%, p=.04).Conclusions Routine use of incisional NPWT was associated with a significant reduction in the incidence of postoperative wound infection and dehiscence.
KW - Deformity
KW - Negative pressure wound therapy
KW - Spine outcomes
KW - Surgical site infections
KW - Wound dehiscence
KW - Wound infection
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U2 - 10.1016/j.spinee.2014.04.011
DO - 10.1016/j.spinee.2014.04.011
M3 - Article
C2 - 24769401
AN - SCOPUS:84919386133
SN - 1529-9430
VL - 14
SP - 2911
EP - 2917
JO - Spine Journal
JF - Spine Journal
IS - 12
ER -