Nesiritide for pulmonary arterial hypertension with decompensated cor pulmonale.

Martha S. Kingman, Brenda S. Thompson, Trixie Newkirk, Fernando Torres

Research output: Contribution to journalArticle

2 Scopus citations


Pulmonary arterial hypertension complicated by decompensated cor pulmonale is a challenging clinical problem with few effective therapeutic options. B-type natriuretic peptide is a pluripotent hormone that promotes diuresis and natriuresis, vasodilates systemic and pulmonary vessels, and reduces circulating levels of endothelin and aldosterone. It may represent a possible therapeutic strategy for decompensated cor pulmonale in the same manner that it is used to treat decompensated left heart failure. The authors report their experience with B-type natriuretic peptide as adjunctive therapy for pulmonary arterial hypertension complicated by decompensated cor pulmonale. A detailed case report is presented followed by the evaluation of a series of 11 cases occurring in eight patients from December 2002 through April 2004.

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalProgress in cardiovascular nursing
Issue number4
StatePublished - Jan 1 2005


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing (miscellaneous)

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