Neural bases of the foreign accent syndrome: A functional magnetic resonance imaging case study

W. F. Katz, D. M. Garst, R. W. Briggs, S. Cheshkov, W. Ringe, K. S. Gopinath, A. Goyal, G. Allen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Foreign accent syndrome (FAS) is a rare disorder characterized by the emergence of a perceived foreign accent following brain damage. Despite decades of study, little is known about the neural substrates involved in this disorder. In this case study, MRI images of the brain were obtained during a speech task for an American English-speaking monolingual female who presented with FAS of unknown etiology and was thought to sound 'Swedish' or 'Eastern European'. On the basis of MR structural imaging, the patient was noted to have frontal lobe atrophy. An fMRI picture-naming task designed to broadly engage the speech motor network revealed predominantly left-hemisphere involvement, including activation of the (1) left superior temporal and medial frontal structures, (2) bilateral subcortical structures and thalamus, and (3) left cerebellum. The results suggest an instance of substantial brain reorganization for speech motor control.

Original languageEnglish (US)
Pages (from-to)199-211
Number of pages13
JournalNeurocase
Volume18
Issue number3
DOIs
StatePublished - Jun 2012

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Sodium Glutamate
Magnetic Resonance Imaging
Brain
Frontal Lobe
Thalamus
Cerebellum
Atrophy
Functional Magnetic Resonance Imaging
Foreign Accent Syndrome
Naming Task
Left Hemisphere
Picture Naming
Sound
Foreign Accent
Etiology
Reorganization
Substrate
Imaging
American English
Brain Damage

Keywords

  • fMRI
  • Foreign accent syndrome
  • Magnetic resonance imaging
  • Speech production

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

Cite this

Neural bases of the foreign accent syndrome : A functional magnetic resonance imaging case study. / Katz, W. F.; Garst, D. M.; Briggs, R. W.; Cheshkov, S.; Ringe, W.; Gopinath, K. S.; Goyal, A.; Allen, G.

In: Neurocase, Vol. 18, No. 3, 06.2012, p. 199-211.

Research output: Contribution to journalArticle

Katz, W. F. ; Garst, D. M. ; Briggs, R. W. ; Cheshkov, S. ; Ringe, W. ; Gopinath, K. S. ; Goyal, A. ; Allen, G. / Neural bases of the foreign accent syndrome : A functional magnetic resonance imaging case study. In: Neurocase. 2012 ; Vol. 18, No. 3. pp. 199-211.
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