Neural bases of the foreign accent syndrome: A functional magnetic resonance imaging case study

W. F. Katz, D. M. Garst, R. W. Briggs, S. Cheshkov, W. Ringe, K. S. Gopinath, A. Goyal, G. Allen

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Foreign accent syndrome (FAS) is a rare disorder characterized by the emergence of a perceived foreign accent following brain damage. Despite decades of study, little is known about the neural substrates involved in this disorder. In this case study, MRI images of the brain were obtained during a speech task for an American English-speaking monolingual female who presented with FAS of unknown etiology and was thought to sound 'Swedish' or 'Eastern European'. On the basis of MR structural imaging, the patient was noted to have frontal lobe atrophy. An fMRI picture-naming task designed to broadly engage the speech motor network revealed predominantly left-hemisphere involvement, including activation of the (1) left superior temporal and medial frontal structures, (2) bilateral subcortical structures and thalamus, and (3) left cerebellum. The results suggest an instance of substantial brain reorganization for speech motor control.

Original languageEnglish (US)
Pages (from-to)199-211
Number of pages13
JournalNeurocase
Volume18
Issue number3
DOIs
Publication statusPublished - Jun 2012

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Keywords

  • fMRI
  • Foreign accent syndrome
  • Magnetic resonance imaging
  • Speech production

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

Cite this

Katz, W. F., Garst, D. M., Briggs, R. W., Cheshkov, S., Ringe, W., Gopinath, K. S., ... Allen, G. (2012). Neural bases of the foreign accent syndrome: A functional magnetic resonance imaging case study. Neurocase, 18(3), 199-211. https://doi.org/10.1080/13554794.2011.588173