Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa

Carrie J. McAdams, Haekyung Jeon-Slaughter, Siobahn Evans, Terry Lohrenz, P. Read Montague, Daniel C. Krawczyk

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other groups, suggesting that recovery may include compensatory neural changes related to social perspectives. The Faces task compared viewing oneself to a stranger. Participants with AN showed elevated activity in the bilateral fusiform gyri for self-images, unlike the weight-recovered and healthy women, suggesting cognitive distortions about physical appearance are a state rather than trait problem in this disease. Because both ill and recovered women showed neural differences related to social self-perception, but only recovered women differed when considering social perspectives, these neurocognitive targets may be particularly important for treatment.

Original languageEnglish (US)
Pages (from-to)1823-1831
Number of pages9
JournalSocial Cognitive and Affective Neuroscience
Volume11
Issue number11
DOIs
StatePublished - Nov 1 2016

Fingerprint

Anorexia Nervosa
Self Concept
Weights and Measures
Diagnostic Self Evaluation
Prefrontal Cortex
Social Perception
Social Identification
Gyrus Cinguli
Temporal Lobe
Cognition
Magnetic Resonance Imaging
Brain

Keywords

  • Eating disorders
  • FMRI
  • Medial prefrontal cortex
  • Psychiatry
  • Self-reflection

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience

Cite this

Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa. / McAdams, Carrie J.; Jeon-Slaughter, Haekyung; Evans, Siobahn; Lohrenz, Terry; Read Montague, P.; Krawczyk, Daniel C.

In: Social Cognitive and Affective Neuroscience, Vol. 11, No. 11, 01.11.2016, p. 1823-1831.

Research output: Contribution to journalArticle

McAdams, Carrie J. ; Jeon-Slaughter, Haekyung ; Evans, Siobahn ; Lohrenz, Terry ; Read Montague, P. ; Krawczyk, Daniel C. / Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa. In: Social Cognitive and Affective Neuroscience. 2016 ; Vol. 11, No. 11. pp. 1823-1831.
@article{60fd4fafb66e4bb9aa8b0ad14bfda160,
title = "Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa",
abstract = "Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other groups, suggesting that recovery may include compensatory neural changes related to social perspectives. The Faces task compared viewing oneself to a stranger. Participants with AN showed elevated activity in the bilateral fusiform gyri for self-images, unlike the weight-recovered and healthy women, suggesting cognitive distortions about physical appearance are a state rather than trait problem in this disease. Because both ill and recovered women showed neural differences related to social self-perception, but only recovered women differed when considering social perspectives, these neurocognitive targets may be particularly important for treatment.",
keywords = "Eating disorders, FMRI, Medial prefrontal cortex, Psychiatry, Self-reflection",
author = "McAdams, {Carrie J.} and Haekyung Jeon-Slaughter and Siobahn Evans and Terry Lohrenz and {Read Montague}, P. and Krawczyk, {Daniel C.}",
year = "2016",
month = "11",
day = "1",
doi = "10.1093/scan/nsw092",
language = "English (US)",
volume = "11",
pages = "1823--1831",
journal = "Social Cognitive and Affective Neuroscience",
issn = "1749-5024",
publisher = "Oxford University Press",
number = "11",

}

TY - JOUR

T1 - Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa

AU - McAdams, Carrie J.

AU - Jeon-Slaughter, Haekyung

AU - Evans, Siobahn

AU - Lohrenz, Terry

AU - Read Montague, P.

AU - Krawczyk, Daniel C.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other groups, suggesting that recovery may include compensatory neural changes related to social perspectives. The Faces task compared viewing oneself to a stranger. Participants with AN showed elevated activity in the bilateral fusiform gyri for self-images, unlike the weight-recovered and healthy women, suggesting cognitive distortions about physical appearance are a state rather than trait problem in this disease. Because both ill and recovered women showed neural differences related to social self-perception, but only recovered women differed when considering social perspectives, these neurocognitive targets may be particularly important for treatment.

AB - Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other groups, suggesting that recovery may include compensatory neural changes related to social perspectives. The Faces task compared viewing oneself to a stranger. Participants with AN showed elevated activity in the bilateral fusiform gyri for self-images, unlike the weight-recovered and healthy women, suggesting cognitive distortions about physical appearance are a state rather than trait problem in this disease. Because both ill and recovered women showed neural differences related to social self-perception, but only recovered women differed when considering social perspectives, these neurocognitive targets may be particularly important for treatment.

KW - Eating disorders

KW - FMRI

KW - Medial prefrontal cortex

KW - Psychiatry

KW - Self-reflection

UR - http://www.scopus.com/inward/record.url?scp=84996836007&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84996836007&partnerID=8YFLogxK

U2 - 10.1093/scan/nsw092

DO - 10.1093/scan/nsw092

M3 - Article

C2 - 27354739

AN - SCOPUS:84996836007

VL - 11

SP - 1823

EP - 1831

JO - Social Cognitive and Affective Neuroscience

JF - Social Cognitive and Affective Neuroscience

SN - 1749-5024

IS - 11

ER -