Neuroblastoma

Titilope A. Ishola, Dai H. Chung

Research output: Contribution to journalReview article

38 Scopus citations

Abstract

Neuroblastomas continue to remain a clinical challenge, despite advances in multimodal therapy. Currently, studies are aimed at novel targets for neuroblastoma directed toward poor prognostic indicators such as the MYCN oncogene and marked angiogenesis. There have also been recent discoveries in neuroblastoma pathogenesis involving epigenetic regulation and retinoic acid therapy. Understanding the intricate complexities of this tumor may lead to innovative agents for more effective combinational therapy.

Original languageEnglish (US)
Pages (from-to)149-156
Number of pages8
JournalSurgical Oncology
Volume16
Issue number3
DOIs
StatePublished - Nov 1 2007
Externally publishedYes

Keywords

  • MYCN
  • Neuroblastoma
  • Tumor regression

ASJC Scopus subject areas

  • Surgery
  • Oncology

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