Neuromodulation for mood and memory: From the engineering bench to the patient bedside

Zhi De Deng, Shawn M. McClintock, Nicodemus E. Oey, Bruce Luber, Sarah H. Lisanby

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Brain stimulation, in the form of electroconvulsive therapy (ECT), has long been a gold standard treatment for depression, but today, the field of neuromodulation is rapidly changing with the advent of newer and more precise tools to alter neuroplasticity and to treat brain-based disorders. Now there are new means to induce focal seizures, as with magnetic seizure therapy (MST), or modifications to ECT. There are also surgical approaches to target brain circuits via implanted stimulators placed in the brain or on cranial nerves. Finally, there are noninvasive subconvulsive approaches for the transcranial application of either electric or magnetic fields. Collectively, these tools have transformed the face of neurotherapeutics and informed our understanding of the brain basis of complex neurobehavioral conditions.

Original languageEnglish (US)
Pages (from-to)38-43
Number of pages6
JournalCurrent Opinion in Neurobiology
Volume30
DOIs
StatePublished - Feb 1 2015

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Electroconvulsive Therapy
Brain
Seizures
Neuronal Plasticity
Cranial Nerves
Brain Diseases
Magnetic Fields
Depression
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuromodulation for mood and memory : From the engineering bench to the patient bedside. / Deng, Zhi De; McClintock, Shawn M.; Oey, Nicodemus E.; Luber, Bruce; Lisanby, Sarah H.

In: Current Opinion in Neurobiology, Vol. 30, 01.02.2015, p. 38-43.

Research output: Contribution to journalReview article

Deng, Zhi De ; McClintock, Shawn M. ; Oey, Nicodemus E. ; Luber, Bruce ; Lisanby, Sarah H. / Neuromodulation for mood and memory : From the engineering bench to the patient bedside. In: Current Opinion in Neurobiology. 2015 ; Vol. 30. pp. 38-43.
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