Neuronal potential and lineage determination by neural stem cells

Research output: Contribution to journalReview article

99 Scopus citations

Abstract

How do neural stem cells ensure that they give rise to the right number and type of neurons at the right time? Over the past year several regulatory mechanisms have been identified, including promotion of neurogenesis by proneural bHLH genes, instruction of gliogenesis by Notch, and cell-intrinsic changes in the neurogenic capacity of stem cells in culture and in vivo.

Original languageEnglish (US)
Pages (from-to)666-672
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume13
Issue number6
DOIs
StatePublished - Dec 1 2001

ASJC Scopus subject areas

  • Cell Biology

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