Neurons in and near insular cortex are responsive to muscular contraction and have sympathetic and/or cardiac-related discharge

Ronaldo M. Ichiyama, Tony G. Waldrop, Gary A. Iwamoto

Research output: Contribution to journalArticle

9 Scopus citations


Insular cortex (IC) is recognized as a potential site for "central command" of cardiorespiratory responses during exercise. Muscular contraction (MC) decreased the discharge rate of most IC neurons. Activity of most contraction sensitive neurons was either not altered by elevating blood pressure or showed a response converse to that of MC. IC may thus have a role in central command but the area is clearly modulated by MC.

Original languageEnglish (US)
Pages (from-to)273-277
Number of pages5
JournalBrain Research
Issue number2
StatePublished - May 22 2004



  • Cardiorespiratory
  • Cardiovascular regulation
  • Cat
  • Endocrine and autonomic regulation
  • Insular cortex
  • Muscular contraction

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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