Neurosurgical applications of the cyanoacrylate adhesives.

B. E. Mickey, D. Samson

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The cyanoacrylate adhesives are a biologically heterogenous group, some of which are potentially valuable additions to the neurosurgical armamentarium. The commercially available cyanoacrylates usually contain the more toxic methyl and ethyl monomers. The safe butyl monomer, isobutyl 2-cyanoacrylate, is approved in the United States by the Food and Drug Administration for investigational use only. Isobutyl 2-cyanoacrylate may prove to be useful for the extravascular reinforcement of intracranial aneurysms and for the intravascular occlusion of carotid-cavernous fistulae. Safe and effective alternatives exist for the management of these two problems. The sealing of certain cerebrospinal fluid fistulae and the intravascular occlusion of certain arteriovenous malformations may be more effectively accomplished with isobutyl 2-cyanoacrylate than with other currently available techniques. The ultimate role of this and of other as yet untested cyanoacrylates in neurosurgery remains to be determined.

Original languageEnglish (US)
Pages (from-to)429-444
Number of pages16
JournalClinical Neurosurgery
Volume28
StatePublished - 1981

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Bucrylate
Cyanoacrylates
Adhesives
Fistula
Poisons
Arteriovenous Malformations
Neurosurgery
Intracranial Aneurysm
United States Food and Drug Administration
Cerebrospinal Fluid

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Neurosurgical applications of the cyanoacrylate adhesives. / Mickey, B. E.; Samson, D.

In: Clinical Neurosurgery, Vol. 28, 1981, p. 429-444.

Research output: Contribution to journalArticle

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