New approaches in medical imaging using plastic scintillating detectors

P. V. Kulkarni; J. A. Anderson; P. P. Antich; J. O. Prior; Y. Zhang; J. Fernando; A. Constantinescu; N. C. Goomer; R. W. Parkey; E. Fenyves; R. C. Chaney; S. C. Srivastava; L. F. Mausner

doi:10.1016/0168-583X(93)95500-5

New approaches in medical imaging using plastic scintillating detectors

P. V. Kulkarni, J. A. Anderson, P. P. Antich, J. O. Prior, Y. Zhang, J. Fernando, A. Constantinescu, N. C. Goomer, R. W. Parkey, E. Fenyves, R. C. Chaney, S. C. Srivastava, L. F. Mausner

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A small animal imaging camera was built in our laboratory, using-fast plastic scintillating detectors (τ = 2-4 ns) and position sensitive photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole collimators were used for ¹²⁵I imaging to achieve submillimeter resolution with scintillating plates of 28 mm radius and 1.5 mm thickness. A high resolution PET module was constructed with arrays of 1.0 mm diameter plastic scintillating fibers. The feasibility of high resolution imaging was demonstrated by the study of brain blood flow in a rat using ¹²⁵I IMP in single photon detection mode and with ⁶⁴Cu PTSM by using PET mode. Construction of single photon and positron emission tomographic imaging systems for small animals and subsequently for human imaging is in progress.

Original language	English (US)
Pages (from-to)	921-925
Number of pages	5
Journal	Nuclear Inst. and Methods in Physics Research, B
Volume	79
Issue number	1-4
DOIs	https://doi.org/10.1016/0168-583X(93)95500-5
State	Published - Jun 2 1993

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

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Kulkarni, P. V., Anderson, J. A., Antich, P. P., Prior, J. O., Zhang, Y., Fernando, J., Constantinescu, A., Goomer, N. C., Parkey, R. W., Fenyves, E., Chaney, R. C., Srivastava, S. C., & Mausner, L. F. (1993). New approaches in medical imaging using plastic scintillating detectors. Nuclear Inst. and Methods in Physics Research, B, 79(1-4), 921-925. https://doi.org/10.1016/0168-583X(93)95500-5

Kulkarni, PV, Anderson, JA, Antich, PP, Prior, JO, Zhang, Y, Fernando, J, Constantinescu, A, Goomer, NC, Parkey, RW, Fenyves, E, Chaney, RC, Srivastava, SC & Mausner, LF 1993, 'New approaches in medical imaging using plastic scintillating detectors', Nuclear Inst. and Methods in Physics Research, B, vol. 79, no. 1-4, pp. 921-925. https://doi.org/10.1016/0168-583X(93)95500-5

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title = "New approaches in medical imaging using plastic scintillating detectors",

abstract = "A small animal imaging camera was built in our laboratory, using-fast plastic scintillating detectors (τ = 2-4 ns) and position sensitive photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole collimators were used for 125I imaging to achieve submillimeter resolution with scintillating plates of 28 mm radius and 1.5 mm thickness. A high resolution PET module was constructed with arrays of 1.0 mm diameter plastic scintillating fibers. The feasibility of high resolution imaging was demonstrated by the study of brain blood flow in a rat using 125I IMP in single photon detection mode and with 64Cu PTSM by using PET mode. Construction of single photon and positron emission tomographic imaging systems for small animals and subsequently for human imaging is in progress.",

author = "Kulkarni, {P. V.} and Anderson, {J. A.} and Antich, {P. P.} and Prior, {J. O.} and Y. Zhang and J. Fernando and A. Constantinescu and Goomer, {N. C.} and Parkey, {R. W.} and E. Fenyves and Chaney, {R. C.} and Srivastava, {S. C.} and Mausner, {L. F.}",

note = "Funding Information: This work supported by Texas Higher Education Coordinating Board (Project #003660-078) at UT Southwestern and U.S. Department of Energy (Contract #DE-AC02-76CH00016) at Brookhaven National Laboratories.",

year = "1993",

month = jun,

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doi = "10.1016/0168-583X(93)95500-5",

language = "English (US)",

volume = "79",

pages = "921--925",

journal = "Nuclear Inst. and Methods in Physics Research, B",

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AU - Kulkarni, P. V.

AU - Anderson, J. A.

AU - Antich, P. P.

AU - Prior, J. O.

AU - Zhang, Y.

AU - Fernando, J.

AU - Constantinescu, A.

AU - Goomer, N. C.

AU - Parkey, R. W.

AU - Fenyves, E.

AU - Chaney, R. C.

AU - Srivastava, S. C.

AU - Mausner, L. F.

N1 - Funding Information: This work supported by Texas Higher Education Coordinating Board (Project #003660-078) at UT Southwestern and U.S. Department of Energy (Contract #DE-AC02-76CH00016) at Brookhaven National Laboratories.

PY - 1993/6/2

Y1 - 1993/6/2

N2 - A small animal imaging camera was built in our laboratory, using-fast plastic scintillating detectors (τ = 2-4 ns) and position sensitive photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole collimators were used for 125I imaging to achieve submillimeter resolution with scintillating plates of 28 mm radius and 1.5 mm thickness. A high resolution PET module was constructed with arrays of 1.0 mm diameter plastic scintillating fibers. The feasibility of high resolution imaging was demonstrated by the study of brain blood flow in a rat using 125I IMP in single photon detection mode and with 64Cu PTSM by using PET mode. Construction of single photon and positron emission tomographic imaging systems for small animals and subsequently for human imaging is in progress.

AB - A small animal imaging camera was built in our laboratory, using-fast plastic scintillating detectors (τ = 2-4 ns) and position sensitive photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole collimators were used for 125I imaging to achieve submillimeter resolution with scintillating plates of 28 mm radius and 1.5 mm thickness. A high resolution PET module was constructed with arrays of 1.0 mm diameter plastic scintillating fibers. The feasibility of high resolution imaging was demonstrated by the study of brain blood flow in a rat using 125I IMP in single photon detection mode and with 64Cu PTSM by using PET mode. Construction of single photon and positron emission tomographic imaging systems for small animals and subsequently for human imaging is in progress.

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New approaches in medical imaging using plastic scintillating detectors

Abstract

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