Abstract
Pathological complete response is observed in nearly 20% of patients with rectal cancer receiving preoperative chemoradiation. Patients who achieve a pathological complete response have better outcomes compared to patients experiencing no response or partial response. Current strategies have not demonstrated a substantial improvement in augmenting the ratio of responders to partial and nonresponders. The following discussion addresses possible strategies of investigation to increase patients achieving a complete obliteration of rectal tumors following neoadjuvant chemoradio therapies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 393-396 |
| Number of pages | 4 |
| Journal | Critical reviews in oncogenesis |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2012 |
Keywords
- Endorectal ultrasound
- Induction chemotherapy
- Laparoscopic LAR
- Preoperative staging
- Rectum
ASJC Scopus subject areas
- Cancer Research