New directions in the preoperative management of adenocarcinoma of the rectum

Research output: Contribution to journalArticle

Abstract

Pathological complete response is observed in nearly 20% of patients with rectal cancer receiving preoperative chemoradiation. Patients who achieve a pathological complete response have better outcomes compared to patients experiencing no response or partial response. Current strategies have not demonstrated a substantial improvement in augmenting the ratio of responders to partial and nonresponders. The following discussion addresses possible strategies of investigation to increase patients achieving a complete obliteration of rectal tumors following neoadjuvant chemoradio therapies.

Original languageEnglish (US)
Pages (from-to)393-396
Number of pages4
JournalCritical reviews in oncogenesis
Volume17
Issue number4
DOIs
StatePublished - Dec 5 2012

Keywords

  • Endorectal ultrasound
  • Induction chemotherapy
  • Laparoscopic LAR
  • Preoperative staging
  • Rectum

ASJC Scopus subject areas

  • Cancer Research

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