TY - JOUR
T1 - New insulin preparations
T2 - A primer for the clinician
AU - Meneghini, Luigi
N1 - Publisher Copyright:
© 2016. Cleveland Clinic Journal of Medicine. All Rights Reserved.
PY - 2016
Y1 - 2016
N2 - The importance of glycemic control in preventing the chronic and devastating complications of diabetes is well established. Insulin administration is an important therapeutic option for managing diabetes, particularly for patients with profound insulin defi ciency. Many insulin formulations are on the market, including short-acting insulin analogues, inhaled insulin, concentrated insulin, and basal insulin. Each category has a unique onset, peak, and duration of action. This article reviews the differing pharmacokinetic and pharmacodynamic properties and safety and effi cacy data, and discusses the implications for clinical practice.
AB - The importance of glycemic control in preventing the chronic and devastating complications of diabetes is well established. Insulin administration is an important therapeutic option for managing diabetes, particularly for patients with profound insulin defi ciency. Many insulin formulations are on the market, including short-acting insulin analogues, inhaled insulin, concentrated insulin, and basal insulin. Each category has a unique onset, peak, and duration of action. This article reviews the differing pharmacokinetic and pharmacodynamic properties and safety and effi cacy data, and discusses the implications for clinical practice.
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U2 - 10.3949/CCJM.83.S1.05
DO - 10.3949/CCJM.83.S1.05
M3 - Article
C2 - 27176680
AN - SCOPUS:85011541179
SN - 0891-1150
VL - 83
SP - 27
EP - 33
JO - Cleveland Clinic journal of medicine
JF - Cleveland Clinic journal of medicine
ER -