Newer antihypertensive agents. When to try them

Norman M Kaplan

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Captopril (Capoten) and minoxidil (Loniten) have recently become generally available for treatment of hypertension and calcium channel blockers, although not yet officially approved for this indication, clearly have potential as antihypertensive agents. Captopril, the only available inhibitor of angiotensin-converting enzyme, is particularly effective in patients with severe, high-renin hypertension. Minoxidil, a potent direct-acting vasodilator, is particularly effective in severely hypertensive patients with concomitant renal insufficiency. Because serious side effects have been noted with both drugs, their use probably should not be considered until other agents have failed. Of the calcium channel blockers, nifedipine (Procardia) seems to have greatest promise as an antihypertensive agent.

Original languageEnglish (US)
Pages (from-to)213-222
Number of pages10
JournalPostgraduate Medicine
Volume73
Issue number1
StatePublished - 1983

Fingerprint

Minoxidil
Captopril
Antihypertensive Agents
Calcium Channel Blockers
Nifedipine
Hypertension
Vasodilator Agents
Angiotensin-Converting Enzyme Inhibitors
Renin
Renal Insufficiency
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Newer antihypertensive agents. When to try them. / Kaplan, Norman M.

In: Postgraduate Medicine, Vol. 73, No. 1, 1983, p. 213-222.

Research output: Contribution to journalArticle

Kaplan, NM 1983, 'Newer antihypertensive agents. When to try them', Postgraduate Medicine, vol. 73, no. 1, pp. 213-222.
Kaplan, Norman M. / Newer antihypertensive agents. When to try them. In: Postgraduate Medicine. 1983 ; Vol. 73, No. 1. pp. 213-222.
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