Inhalation of 60% nitrous oxide in oxygen by seven adult male volunteers for 60 min was found to increase significantly polymorphonuclear leucocyte (PMN) chemotaxis, but not to influence total white or PMN blood cell counts. Also, the addition of morphine 0.2 mg kg-11 i.v. during the breathing of nitrous oxide did not alter any variable. These results indicate that nitrous oxide and nitrous oxide in combination with morphine do not depress PMN chemotaxis.
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine