Noise reduction for low-dose single-slice helical CT sinograms

Jing Wang, Tianfang Li, Hongbing Lu, Zhengrong Liang

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Helical computed tomography (HCT) has several advantages over conventional step-and-shoot CT for imaging a relatively large object, especially for dynamic studies. However, HCT may increase X-ray exposure significantly. This work aims to reduce the radiation by lowering X-ray tube current (mA) and filtering low-mA (or dose) sinogram noise of HCT. The noise reduction method is based on three observations on HCT: (1) the axial sampling of HCT projections is nearly continuous as detection system rotates; (2) the noise distribution in sinogram space is nearly a Gaussian after system calibration (including logarithmic transform); and (3) the relationship between the calibrated data mean and variance can be expressed as an exponential functional across the fleld-of-view. Based on the second and third observations, a penalized weighted least-squares (PWLS) solution is an optimal choice, where the weight is given by the mean-variance relationship. The first observation encourages the use of Karhunen-Loéve (KL) transform along the axial direction because of the associated correlation. In the KL domain, the eigenvalue of each principal component and the derived data variance provide the signal-to-noise ratio (SNR) information, resulting in a SNR-adaptive noise reduction. The KL-PWLS noise-reduction method was implemented analytically for efficient restoration of large volume HCT sinograms. Simulation studies showed a noticeable improvement, in terms of image quality and defect detectability, of the proposed noise-reduction method over the Ordered-Subsets Expectation-Maximization reconstruction and the conventional low-pass noise filtering with optimal cutoff frequency and/or other filter parameters.

Original languageEnglish (US)
Article number1645020
Pages (from-to)1230-1237
Number of pages8
JournalIEEE Transactions on Nuclear Science
Volume53
Issue number3
DOIs
StatePublished - Jun 2006

Fingerprint

Noise abatement
noise reduction
Tomography
tomography
dosage
Signal to noise ratio
signal to noise ratios
X ray tubes
Cutoff frequency
Set theory
Acoustic noise
restoration
Image quality
Restoration
set theory
x rays
eigenvalues
cut-off
projection
sampling

Keywords

  • Helical computed tomography
  • KL transforms
  • Penalized weighted least-squares
  • Sinogram noise reduction

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

Noise reduction for low-dose single-slice helical CT sinograms. / Wang, Jing; Li, Tianfang; Lu, Hongbing; Liang, Zhengrong.

In: IEEE Transactions on Nuclear Science, Vol. 53, No. 3, 1645020, 06.2006, p. 1230-1237.

Research output: Contribution to journalArticle

Wang, Jing ; Li, Tianfang ; Lu, Hongbing ; Liang, Zhengrong. / Noise reduction for low-dose single-slice helical CT sinograms. In: IEEE Transactions on Nuclear Science. 2006 ; Vol. 53, No. 3. pp. 1230-1237.
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