Non-invasive evaluation of bladder outlet obstruction in men suspected of benign prostatic hyperplasia: Usefulness of the D index

Françoise A. Valentini, Pierre P. Nelson, Philippe E. Zimmern

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective: To compare a new index of voiding dysfunction (D) based purely on free uroflow vs. Abrams-Griffiths (A-G) number obtained from intubated flow, for classification of bladder outlet obstruction in men. Patients and Methods: Urodynamic tracings of 60 non-neurological patients (30 before transurethral resection of the prostate and of 30 men suspected of benign prostatic hyperplasia included in a medical therapy trial) were retrospectively analyzed. The Valentini-Besson-Nelson model was used to evaluate the value of the D index. A-G was obtained from intubated flows. Obstruction was defined as D > 32.5 cm H2O (translation of A-G criterion). Results: D showed 82.05% sensitivity with 66.66% specificity; the positive predictive value was 82.05% and the negative predictive value 66.66% for the whole population, 83.3 vs. 80.9% sensitivity with 58.3 vs. 77.7% specificity for pre-transurethral resection of the prostate vs. medical therapy group. Conclusion: D index which can be obtained from a free uroflow appears as a valuable alternative to invasive urodynamic investigations when the diagnosis of bladder outlet obstruction needs to be more solidly established before a treatment decision or in men suspected of benign prostatic hyperplasia who elect for watchful waiting.

Original languageEnglish (US)
Pages (from-to)124-128
Number of pages5
JournalCurrent Urology
Volume6
Issue number3
DOIs
StatePublished - Jan 2013

Keywords

  • Benign prostatic hyperplasia
  • Bladder outlet obstruction
  • Free uroflow
  • Non invasive testing
  • Voiding dysfunction index

ASJC Scopus subject areas

  • Reproductive Medicine
  • Oncology
  • Urology

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