Nonconvulsive status epilepticus resulting from Jarisch-Herxheimer reaction in a patient with neurosyphilis

Suleiman Kojan, Paul C. Van Ness, Ramon Diaz-Arrastia

Research output: Contribution to journalArticle

14 Scopus citations


We report a case of Jarisch-Herxheimer reaction-in a patient with neurosyphilis, which was complicated by nonconvulsive status epilepticus. The EEG features suggested a focal seizure onset, although the patient's MRI was normal. JHR is common in the treatment of neurosyphilis, but usually produces only transient systemic constitutional symptoms. Neurologic deterioration is rare, but can be dramatic, as in our patient. NCSE should be considered as an explanation for persistent obtundation and transient focal neurologic findings in this setting.

Original languageEnglish (US)
Pages (from-to)138-140
Number of pages3
JournalClinical EEG Electroencephalography
Issue number3
Publication statusPublished - Jul 2000



  • Jarisch-Herxheimer Reaction
  • Neurosyphilis
  • Nonconvulsive Status Epilepticus

ASJC Scopus subject areas

  • Clinical Neurology

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