Abstract
Imaging small blood vessels and measuring their functional information in finger joint are still challenges for clinical imaging modalities. In this study, we developed a multi-transducer functional photoacoustic tomography (PAT) system and successfully imaged human finger-joint vessels from ∼1 mm to <0.2 mm in diameter. In addition, the oxygen saturation (SO2) values of these vessels were also measured. Our results demonstrate that PAT can provide both anatomical and functional information of individual finger-joint vessels with different sizes, which might help the study of finger-joint diseases, such as rheumatoid arthritis.
Original language | English (US) |
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Article number | 061009 |
Journal | Journal of biomedical optics |
Volume | 21 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2016 |
Externally published | Yes |
Keywords
- Human finger joints
- Medical imaging
- Oxygen saturation
- Photoacoustic tomography
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Biomedical Engineering