Nonserious Infections. Should There Be Cause for Serious Concerns?

Kathryn H. Dao, Morley Herbert, Nadia Habal, John J. Cush

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Nonserious infections (NSIE) as colds, flu syndromes, and urinary tract infection, are the most common infections seen in patients with immune mediated inflammatory diseases. Yet, little is known about the impact of immunosuppression, particularly with tumor necrosis factor inhibitors (TNFi), on these infections. A systemic review of large, randomized controlled trials was conducted to identify incidence, types, and outcomes of NSIE associated with the most commonly prescribed TNFi: adalimumab, etanercept, and infliximab.

Original languageEnglish (US)
Pages (from-to)707-725
Number of pages19
JournalRheumatic Disease Clinics of North America
Volume38
Issue number4
DOIs
StatePublished - Nov 1 2012
Externally publishedYes

Keywords

  • Adalimumab
  • Anti-TNF
  • Etanercept
  • Infliximab
  • Nonserious infections
  • Rheumatoid arthritis
  • Safety

ASJC Scopus subject areas

  • Rheumatology

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