Norepinephrine-induced acute renal failure: A reversible ischemic model of acute renal failure

R. E. Cronin, A. M. Erickson, A. de Torrente, K. M. McDonald, R. W. Schrier

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Abstract

This study has defined conditions whereby a reversible form of ischemia-induced acute renal failure ARF can be produced in the dog. Unlike previous studies which examined the acute phase of nor-epinephrine NE-induced acute renal failure ARF, this study demonstrates the feasibility of using the model for the longitudinal study of nor-epinephrine ARF. Such a model may be useful in studying the pathologic and physiologic changes which occur during different phases of acute renal failure ARF. Perhaps most important, this model should also provide a setting in which treatment measures, either prophylactic or therapeutic for acute renal failure ARF, can be examined.

Original languageEnglish (US)
Pages (from-to)187-190
Number of pages4
JournalKidney International
Volume14
Issue number2
Publication statusPublished - 1978

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ASJC Scopus subject areas

  • Nephrology

Cite this

Cronin, R. E., Erickson, A. M., de Torrente, A., McDonald, K. M., & Schrier, R. W. (1978). Norepinephrine-induced acute renal failure: A reversible ischemic model of acute renal failure. Kidney International, 14(2), 187-190.