Novel method of reducing ketones using sodium hydroxide in isopropanol

Daniel R. Zuidema, Katherine J. Wert, Sarah L. Williams, Samuel T. Chill, Kimberly L. Holte, Nathanael K. Kokes, Robert C. Mebane

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Ketones are readily reduced to secondary alcohols with sodium hydroxide in refluxing isopropanol.

Original languageEnglish (US)
Pages (from-to)1187-1191
Number of pages5
JournalSynthetic Communications
Volume40
Issue number8
DOIs
StatePublished - Jan 1 2010
Externally publishedYes

Keywords

  • Hydrogen transfer
  • Ketone reduction
  • Preparation of secondary alcohols
  • Sodium hydroxide

ASJC Scopus subject areas

  • Organic Chemistry

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