Novel targeting and activation strategies for photodynamic therapy

Juan Chen; Ian R. Corbin; Gang Zheng

doi:10.1007/978-0-387-71809-5_13

Novel targeting and activation strategies for photodynamic therapy

Juan Chen, Ian R. Corbin, Gang Zheng

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

Original language	English (US)
Title of host publication	Proceedings of Light-Activated Tissue Regeneration and Therapy Conference
Pages	127-147
Number of pages	21
DOIs	https://doi.org/10.1007/978-0-387-71809-5_13
State	Published - Dec 1 2008
Event	2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007 - Tomar, Portugal Duration: Jun 24 2007 → Jun 29 2007

Publication series

Name	Lecture Notes in Electrical Engineering
Volume	12 LNEE
ISSN (Print)	1876-1100
ISSN (Electronic)	1876-1119

Other

Other	2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007
Country	Portugal
City	Tomar
Period	6/24/07 → 6/29/07

Keywords

High density lipoproteins
Low density lipoproteins
Lysine residues
Molecular beacons
Nanoparticles
Receptors

ASJC Scopus subject areas

Industrial and Manufacturing Engineering

Access to Document

10.1007/978-0-387-71809-5_13

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Cite this

Chen, J., Corbin, I. R., & Zheng, G. (2008). Novel targeting and activation strategies for photodynamic therapy. In Proceedings of Light-Activated Tissue Regeneration and Therapy Conference (pp. 127-147). (Lecture Notes in Electrical Engineering; Vol. 12 LNEE). https://doi.org/10.1007/978-0-387-71809-5_13

Chen, J, Corbin, IR & Zheng, G 2008, Novel targeting and activation strategies for photodynamic therapy. in Proceedings of Light-Activated Tissue Regeneration and Therapy Conference. Lecture Notes in Electrical Engineering, vol. 12 LNEE, pp. 127-147, 2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007, Tomar, Portugal, 6/24/07. https://doi.org/10.1007/978-0-387-71809-5_13

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