Novel targeting and activation strategies for photodynamic therapy

Juan Chen, Ian R. Corbin, Gang Zheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

Original languageEnglish (US)
Title of host publicationProceedings of Light-Activated Tissue Regeneration and Therapy Conference
Pages127-147
Number of pages21
DOIs
StatePublished - Dec 1 2008
Event2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007 - Tomar, Portugal
Duration: Jun 24 2007Jun 29 2007

Publication series

NameLecture Notes in Electrical Engineering
Volume12 LNEE
ISSN (Print)1876-1100
ISSN (Electronic)1876-1119

Other

Other2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007
CountryPortugal
CityTomar
Period6/24/076/29/07

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Keywords

  • High density lipoproteins
  • Low density lipoproteins
  • Lysine residues
  • Molecular beacons
  • Nanoparticles
  • Receptors

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering

Cite this

Chen, J., Corbin, I. R., & Zheng, G. (2008). Novel targeting and activation strategies for photodynamic therapy. In Proceedings of Light-Activated Tissue Regeneration and Therapy Conference (pp. 127-147). (Lecture Notes in Electrical Engineering; Vol. 12 LNEE). https://doi.org/10.1007/978-0-387-71809-5_13