Novel therapies for Hodgkin lymphoma

Research output: Contribution to journalArticle

Abstract

In recent years, improved understanding of the biology of Hodgkin lymphoma (HL) has uncovered many potential targets for the treatment of this disease. Clarification of the B-cell origin of the Hodgkin Reed Sternberg (HRS) cell and of the complex interactions between the HRS cell and the HL microenvironment have provided new insights into the pathophysiology of HL and identified extracellular and intracellular molecules which are essential for HRS survival. New agents directed at these molecules are now in early phase clinical trials.

Original languageEnglish (US)
Pages (from-to)23-29
Number of pages7
JournalTherapeutic Advances in Hematology
Volume1
Issue number1
DOIs
StatePublished - Dec 2010
Externally publishedYes

Keywords

  • Hodgkin lymphoma
  • new agents
  • targeted therapy

ASJC Scopus subject areas

  • Hematology

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